Evidence map›Paper›PMID 37877260›Full record

Trial reportPain management2023

The impact of intraoperative N-acetylcysteine on opioid consumption following spine surgery: a randomized pilot trial.

Sylvia H Wilson, Joel M Sirianni, Kathryn H Bridges, Bethany J Wolf, Isabella E Valente, Michael D Scofield

Open access · greenAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Pain management, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Sylvia H WilsonDepartment of Anesthesia & Perioperative Medicine, Medical University of South Carolina, Charleston, SC 29425, USA.ORCID 0000-0003-4747-6009
Joel M SirianniDepartment of Anesthesia & Perioperative Medicine, Medical University of South Carolina, Charleston, SC 29425, USA.ORCID 0000-0003-3360-6087
Kathryn H BridgesDepartment of Anesthesia & Perioperative Medicine, Medical University of South Carolina, Charleston, SC 29425, USA.ORCID 0000-0002-7467-277X
Bethany J WolfPublic Health Sciences, Medical University of South Carolina, Charleston, SC 29425, USA.ORCID 0000-0002-7124-5158
Isabella E ValenteCollege of Medicine, Medical University of South Carolina, Charleston, SC 29425, USA.ORCID 0000-0003-3355-0423
Michael D ScofieldDepartment of Anesthesia & Perioperative Medicine, Medical University of South Carolina, Charleston, SC 29425, USA.ORCID 0000-0002-2330-6999
Medical University of South Carolina · US

Funding

South Carolina Clinical & Translational Research Institute (SCTR)UL1TR001450 · NCATS · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI BRADY, KATHLEEN T., FLUME, PATRICK A · 2015 to 2024
$41.1M
Nitrergic interneurons and cue-induced cocaine seekingR01DA054154 · NIDA · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI SCOFIELD, MICHAEL DAVID · 2021 to 2025
$1.7M
NCATS NIH HHS UL1 TR001450NCATS NIH HHS UL1TR001450NIDA NIH HHS R01 DA054154
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AcetylcysteineAnalgesics, OpioidAdultDouble-Blind MethodHumansPilot ProjectsPostoperative PainProspective StudiesAcetylcysteineAnalgesics, Opioidacetylcysteineanalgesiaanti-inflammatory agentsneurosurgical proceduresorthopedic procedurespain management

Identifiers

PMID37877260
PMCPMC10694787
OpenAlexW4387931904

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.