Evidence map›Paper›PMID 37876996›Full record

ArticleEClinicalMedicine2023

Global incidence and prevalence of autoimmune hepatitis, 1970-2022: a systematic review and meta-analysis.

Jong Woo Hahn, Hye Ran Yang, Jin Soo Moon, Ju Young Chang, Kwanjoo Lee, Gi Ae Kim, Masoud Rahmati, Ai Koyanagi, Lee Smith, Min Seo Kim and 10 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in EClinicalMedicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 67 papers, 9 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
67citing papers in PubMed, 9 pooled it
17.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

67 citing papers in PubMed, 9 syntheses or guidelines pooled it, 84 citations in OpenAlex.

  1. Pooled it
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  3. Comparative Effectiveness of Mycophenolate Mofetil and Tacrolimus as a Second-Line Therapy for Autoimmune Hepatitis: A Systematic Review and Meta-Analysis.Medical principles and practice : international journal of the Kuwait University, Health Science Centre · 2026
    Pooled it
  4. Guideline
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  10. Article
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  12. Review
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  16. Autoantibodies in the follow-up of autoimmune hepatitis.Journal of translational autoimmunity · 2026
    Review
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  18. Article
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  20. Article

7 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 10 institutions in 7 countries.

Jong Woo HahnDepartment of Paediatrics, Seoul National University College of Medicine, Seoul, South Korea.
Hye Ran YangDepartment of Paediatrics, Seoul National University College of Medicine, Seoul, South Korea.
Jin Soo MoonDepartment of Paediatrics, Seoul National University College of Medicine, Seoul, South Korea.
Ju Young ChangDepartment of Paediatrics, Seoul National University College of Medicine, Seoul, South Korea.
Kwanjoo LeeDigestive Disease Centre, CHA Bundang Medical Centre, CHA University School of Medicine, Seongnam, South Korea.
Gi Ae KimDepartment of Internal Medicine, Kyung Hee University School of Medicine, Seoul, South Korea.
Masoud RahmatiDepartment of Physical Education and Sport Sciences, Faculty of Literature and Human Sciences, Lorestan University, Khoramabad, Iran.
Ai KoyanagiResearch and Development Unit, Parc Sanitari Sant Joan de Deu, Barcelona, Spain.
Lee SmithCentre for Health, Performance and Wellbeing, Anglia Ruskin University, Cambridge, UK.
Min Seo KimCardiovascular Disease Initiative, Broad Institute of MIT and Harvard, Cambridge, MA, USA.
Guillermo F López SánchezDivision of Preventive Medicine and Public Health, Department of Public Health Sciences, School of Medicine, University of Murcia, Murcia, Spain.
Dragioti ElenaPain and Rehabilitation Centre, Department of Medical and Health Sciences, Linköping University, Linköping, Sweden.
Ju-Young ShinSchool of Pharmacy, Sungkyunkwan University, Suwon, South Korea.
Jae Il ShinDepartment of Paediatrics, Yonsei University College of Medicine, Seoul, South Korea.
Rosie KwonCentre for Digital Health, Medical Science Research Institute, Kyung Hee University College of Medicine, Seoul, South Korea.
Soeun KimCentre for Digital Health, Medical Science Research Institute, Kyung Hee University College of Medicine, Seoul, South Korea.
Hyeon Jin KimCentre for Digital Health, Medical Science Research Institute, Kyung Hee University College of Medicine, Seoul, South Korea.
Hojae LeeCentre for Digital Health, Medical Science Research Institute, Kyung Hee University College of Medicine, Seoul, South Korea.
Jae Sung KoDepartment of Paediatrics, Seoul National University College of Medicine, Seoul, South Korea.
Dong Keon YonCentre for Digital Health, Medical Science Research Institute, Kyung Hee University College of Medicine, Seoul, South Korea.
Kyung Hee University · KRSeoul National University · KRYonsei University · KRAnglia Ruskin University · GBBroad Institute · USCHA University Bundang Medical Center · KRLinköping University · SEParc Sanitari Sant Joan de Déu · ESUniversidad de Murcia · ESVali Asr University of Rafsanjan · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Autoimmune hepatitis (AIH) varies significantly in incidence and prevalence across countries and regions. We aimed to examine global, regional, and national trends in incidence and prevalence of AIH from 1970 to 2022. Methods: We conducted a thorough search of the PubMed/MEDLINE, Embase, CINAHL, Google Scholar, and Cochrane databases from database inception to August 9, 2023, using the search term "autoimmune hepatitis" in combination with "incidence," "prevalence," or "trend." Only general population-based observational studies with larger samples sizes were considered for inclusion. Studies that recruited convenience samples, and those with fewer than 50 participants were excluded. Summary data were extracted from published reports. A random effects model was used and pooled estimates with 95% CI were used to calculate the incidence and prevalence of AIH. Heterogeneity was evaluated using the Findings: A total of 37 eligible studies, encompassing more than 239 million participants and 55,839 patients with AIH from 18 countries across five continents, were included in the analysis. Global pooled incidence and prevalence of AIH were found to be 1.28 cases per 100,000 inhabitant-years (95% CI, 1.01-1.63, Interpretation: AIH incidence and prevalence have increased significantly and exhibit substantial variation across regions worldwide. Further research is required to assess the incidence and prevalence of AIH, specifically in South America and Africa. Funding: National Research Foundation of Korea.

Indexed as

Autoimmune hepatitisGlobal trendIncidencePrevalenceSystematic review and meta-analysis

Identifiers

PMID37876996
PMCPMC10590724
OpenAlexW4387722553

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.