Evidence map›Paper›PMID 37876887›Full record

ArticleCJC open2023

Is Transcatheter Aortic Valve Replacement Futile in Patients Over Ninety Years of Age?

Jérémy Bernard, Roxanne St-Louis, Mathieu Robichaud, Dimitri Kalavrouziotis, Éric Dumont, Jean-Michel Paradis, Shervin Babaki, Josep Rodés-Cabau, Siamak Mohammadi

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in CJC open, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Jérémy BernardDivision of Cardiology, Institut universitaire de cardiologie et de pneumologie de Québec (Université Laval/Quebec Heart and Lung Institute), Laval University, Quebec City, Quebec, Canada.
Roxanne St-LouisDivision of Cardiac Surgery, Institut universitaire de cardiologie et de pneumologie de Québec (Université Laval/Quebec Heart and Lung Institute), Laval University, Quebec City, Quebec, Canada.
Mathieu RobichaudDivision of Cardiology, Institut universitaire de cardiologie et de pneumologie de Québec (Université Laval/Quebec Heart and Lung Institute), Laval University, Quebec City, Quebec, Canada.
Dimitri KalavrouziotisDivision of Cardiac Surgery, Institut universitaire de cardiologie et de pneumologie de Québec (Université Laval/Quebec Heart and Lung Institute), Laval University, Quebec City, Quebec, Canada.
Éric DumontDivision of Cardiac Surgery, Institut universitaire de cardiologie et de pneumologie de Québec (Université Laval/Quebec Heart and Lung Institute), Laval University, Quebec City, Quebec, Canada.
Jean-Michel ParadisDivision of Cardiology, Institut universitaire de cardiologie et de pneumologie de Québec (Université Laval/Quebec Heart and Lung Institute), Laval University, Quebec City, Quebec, Canada.
Shervin BabakiDivision of Research, Institut universitaire de cardiologie et de pneumologie de Québec (Université Laval/Quebec Heart and Lung Institute), Laval University, Quebec City, Quebec, Canada.
Josep Rodés-CabauDivision of Cardiology, Institut universitaire de cardiologie et de pneumologie de Québec (Université Laval/Quebec Heart and Lung Institute), Laval University, Quebec City, Quebec, Canada.
Siamak MohammadiDivision of Cardiac Surgery, Institut universitaire de cardiologie et de pneumologie de Québec (Université Laval/Quebec Heart and Lung Institute), Laval University, Quebec City, Quebec, Canada.
Institut universitaire de cardiologie et de pneumologie de Québec · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Clinical outcomes and quality of life (QoL) indices are not well described after transcatheter aortic valve replacement (TAVR) in patients aged ≥ 90 years. Methods: We conducted a retrospective cohort study of TAVR among nonagenarian patients between 2008 and 2020. The survival of TAVR patients among nonagenarians was compared to the provincial estimated survival for an age- and sex-matched general population. QoL was assessed up to 1 year postintervention, using standardized questionnaires. Results: During the study period, n = 268 patients aged ≥ 90 years were evaluated for severe aortic stenosis. TAVR was performed in n = 171 (48% female; median [IQR] Rockwood Clinical Frailty Scale score: 4 [3-4]); n = 84 underwent medical therapy; and n = 13 underwent surgical aortic valve replacement. Survival was significantly better following TAVR, compared to that after MT (adjusted hazard ratio [95% CI]: 1.99 [1.37-2.88], Conclusions: Nonagenarians undergoing TAVR experience a slightly better survival rate, compared to that of an age- and sex-matched general population, and they have significant improvements in functional status and several QoL indices following the procedure.

Identifiers

PMID37876887
PMCPMC10591129
OpenAlexW4385688299

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.