Evidence map›Paper›PMID 37876521›Full record

ArticleFrontiers in pediatrics2023

Respiratory patterns in spontaneously breathing near-term lambs delivered by caesarean section under spinal anaesthesia.

I M Davies, K J Crossley, E V McGillick, I Nitsos, K Rodgers, A Thiel, V A Zahra, A B Te Pas, S B Hooper

Abstract read
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Article in Frontiers in pediatrics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

I M DaviesThe Ritchie Centre, Hudson Institute of Medical Research, Melbourne, VIC, Australia.
K J CrossleyThe Ritchie Centre, Hudson Institute of Medical Research, Melbourne, VIC, Australia.
E V McGillickThe Ritchie Centre, Hudson Institute of Medical Research, Melbourne, VIC, Australia.
I NitsosThe Ritchie Centre, Hudson Institute of Medical Research, Melbourne, VIC, Australia.
K RodgersThe Ritchie Centre, Hudson Institute of Medical Research, Melbourne, VIC, Australia.
A ThielThe Ritchie Centre, Hudson Institute of Medical Research, Melbourne, VIC, Australia.
V A ZahraThe Ritchie Centre, Hudson Institute of Medical Research, Melbourne, VIC, Australia.
A B Te PasDivision of Neonatology, Department of Pediatrics, Leiden University Medical Center, Leiden, Netherlands.
S B HooperThe Ritchie Centre, Hudson Institute of Medical Research, Melbourne, VIC, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: The transition to newborn life has typically been studied in intubated and mechanically ventilated newborn lambs delivered via caesarean section (CS) under general anaesthesia. As a result, little is known of the spontaneous breathing patterns in lambs at birth, particularly those at risk of developing respiratory distress (RD). We have developed a method for delivering spontaneously breathing near-term lambs to characterise their breathing patterns in the immediate newborn period. Methods: At 137-8 days gestation (2-3 days prior to delivery; term ∼147 days), fetal lambs ( Results: Newborn lambs display significant heterogeneity in respiratory patterns in the immediate newborn period that change with time after birth. Seven distinct breathing patterns were identified including: (i) quiet (tidal) breathing, (ii) breathing during active periods, (iii) breathing during oral feeding, (iv) tachypnoea, (v) expiratory braking manoeuvres, (vi) expiratory pauses or holding, and (vii) step changes in ventilation. Conclusions: We have described normal respiratory behaviour in newborn lambs, in order to identify respiratory behaviours that are indicative of RD in term newborn infants.

Indexed as

breathing patternscaesarean sectionnewbornnewborn lambsrespiratory distress

Identifiers

PMID37876521
PMCPMC10590898

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.