Evidence map›Paper›PMID 37876509›Full record

ArticleRomanian journal of ophthalmology

Biomarkers of ocular allergy and dry eye disease.

Mihail Zemba, Mihai-Alexandru Ionescu, Ruxandra Angela Pîrvulescu, Otilia-Maria Dumitrescu, Brănişteanu Daniel-Constantin, Mădălina Radu, Alina-Cristina Stamate, Sînziana Istrate

Open access · bronzeAbstract read
In one paragraph

Article in Romanian journal of ophthalmology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
5.2field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Mihail ZembaDepartment of Ophthalmology, "Carol Davila" University of Medicine and Pharmacy, Bucharest, Romania.
Mihai-Alexandru IonescuDepartment of Ophthalmology, "Dr. Carol Davila" Central Military Emergency University Hospital, Bucharest, Romania.
Ruxandra Angela PîrvulescuDepartment of Ophthalmology, "Carol Davila" University of Medicine and Pharmacy, Bucharest, Romania.
Otilia-Maria DumitrescuDepartment of Ophthalmology, "Dr. Carol Davila" Central Military Emergency University Hospital, Bucharest, Romania.
Brănişteanu Daniel-ConstantinDepartment of Ophthalmology, "Grigore T. Popa" University of Medicine and Pharmacy, Iaşi, Romania.
Mădălina RaduDepartment of Ophthalmology, "Dr. Carol Davila" Central Military Emergency University Hospital, Bucharest, Romania.
Alina-Cristina StamateDepartment of Ophthalmology, "Carol Davila" University of Medicine and Pharmacy, Bucharest, Romania.
Sînziana IstrateDepartment of Ophthalmology, "Carol Davila" University of Medicine and Pharmacy, Bucharest, Romania.
Carol Davila University of Medicine and Pharmacy · ROGrigore T. Popa University of Medicine and Pharmacy · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The most common disorders of the ocular surface are dry eye disease (DED) and ocular allergy (OA). These conditions are frequently coexisting with or without a clinical overlap and can cause a severe impact on the patient's quality of life. Therefore, it can sometimes be hard to distinguish between DED and OA because similar changes and manifestations may be present. Atopic patients can also develop DED, which can aggravate their manifestations. Moreover, patients with DED can develop ocular allergies, so these two pathological entities of the ocular surface can be considered as mutual conditions that share the same background. Nowadays, by using different techniques to collect tissue from ocular surfaces, the changes in molecular homeostasis can be detected and this can lead to a precise diagnosis. The article provides an up-to-date review of the various ocular surface biomarkers that have been identified in DED, OA, or both conditions.

Indexed as

Conjunctivitis, AllergicDry Eye SyndromesAnnexinsBiomarkersCalcitoninCalcitonin Gene-Related PeptideChemokinesCytokinesHumansLigandsProlineQuality of LifeTumor Necrosis Factor-alphaAnnexinsBiomarkersCalcitoninCalcitonin Gene-Related PeptideChemokinesCytokinesLigandsProlineTumor Necrosis Factor-alphabiomarkerdiagnostic biomarkerdry eye diseaseocular allergyprognostic biomarkersSjögren’s syndrome

Identifiers

PMID37876509
PMCPMC10591437
OpenAlexW4387930884

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.