Evidence map›Paper›PMID 37876458›Full record

ArticleHeliyon2023

Severe intestinal barrier damage in HIV-infected immunological non-responders.

Xiao-Yan Guo, Yun-Tian Guo, Ze-Rui Wang, Yan-Mei Jiao, Yue Hu, Li-Na Fan, Rui-Qin Cheng, Meng-Meng Qu, Chao Zhang, Jin-Wen Song and 9 more

Open access · goldAbstract read
In one paragraph

Article in Heliyon, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Article
  6. Article
  7. Article
  8. [Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2025
    Article
  9. Article
  10. Review
  11. Alterations of the Intestinal Mucosal Barrier and Gut Fungal Microbiome in Asymptomatic HIV-Infected Patients.The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2024
    Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 5 institutions in 1 country.

Xiao-Yan GuoBeijing Ditan Hospital, Capital Medical University, Beijing, China.
Yun-Tian GuoSenior Department of Infectious Diseases, the Fifth Medical Centre of Chinese PLA General Hospital, National Clinical Research Center for Infectious Diseases, Beijing, China.
Ze-Rui WangDepartment of Gastroenterology, First Medical Center of Chinese PLA General Hospital, Beijing, China.
Yan-Mei JiaoSenior Department of Infectious Diseases, the Fifth Medical Centre of Chinese PLA General Hospital, National Clinical Research Center for Infectious Diseases, Beijing, China.
Yue HuDepartment of Infectious Diseases, Tianjin Second People's Hospital, Tianjin, China.
Li-Na FanDepartment of Infectious Diseases, Tianjin Second People's Hospital, Tianjin, China.
Rui-Qin ChengTianjin Bright Eye Hospital, Tianjin, China.
Meng-Meng QuSenior Department of Infectious Diseases, the Fifth Medical Centre of Chinese PLA General Hospital, National Clinical Research Center for Infectious Diseases, Beijing, China.
Chao ZhangSenior Department of Infectious Diseases, the Fifth Medical Centre of Chinese PLA General Hospital, National Clinical Research Center for Infectious Diseases, Beijing, China.
Jin-Wen SongSenior Department of Infectious Diseases, the Fifth Medical Centre of Chinese PLA General Hospital, National Clinical Research Center for Infectious Diseases, Beijing, China.
Ruo-Nan XuSenior Department of Infectious Diseases, the Fifth Medical Centre of Chinese PLA General Hospital, National Clinical Research Center for Infectious Diseases, Beijing, China.
Xing FanSenior Department of Infectious Diseases, the Fifth Medical Centre of Chinese PLA General Hospital, National Clinical Research Center for Infectious Diseases, Beijing, China.
Wen XuSenior Department of Infectious Diseases, the Fifth Medical Centre of Chinese PLA General Hospital, National Clinical Research Center for Infectious Diseases, Beijing, China.
Ji-Yuan ZhangSenior Department of Infectious Diseases, the Fifth Medical Centre of Chinese PLA General Hospital, National Clinical Research Center for Infectious Diseases, Beijing, China.
Bing-Ke BaiSenior Department of Infectious Diseases, the Fifth Medical Centre of Chinese PLA General Hospital, National Clinical Research Center for Infectious Diseases, Beijing, China.
En-Qiang LinghuDepartment of Gastroenterology, First Medical Center of Chinese PLA General Hospital, Beijing, China.
Yao-Kai ChenDepartment of Infectious Disease, Chongqing Public Health Medical Center, Chongqing, China.
Ping MaDepartment of Infectious Diseases, Tianjin Second People's Hospital, Tianjin, China.
Fu-Sheng WangBeijing Ditan Hospital, Capital Medical University, Beijing, China.
Chinese PLA General Hospital · CNTianjin People's Hospital · CNCapital Medical University · CNChongqing Public Health Medical Center · CNTianjin Medical University Eye Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The intestinal epithelial barrier plays an important role during human immunodeficiency virus (HIV) disease progression. However, the extent to which the intestinal epithelial barrier is damaged in immunological non-responders (INRs) and immunological responders (IRs) is largely unknown. In this study, we investigated and compared the levels of intestinal gland damage and related molecules, including the tight junction protein claudin-1, apoptosis marker caspase-3, HIV DNA, CD4

Indexed as

HIVImmunological non-respondersImmunological respondersIntestinal damage

Identifiers

PMID37876458
PMCPMC10590933
OpenAlexW4387580284

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.