ArticleDeutsches Arzteblatt international2024
Childhood Trauma and Somatic and Mental Illness in Adulthood.
Article in Deutsches Arzteblatt international, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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16 citing papers in PubMed, 19 citations in OpenAlex.
- Evaluating psychosis-specific effects of trauma exposure in early-onset and adult-onset psychosis.Psychological medicine · 2026Article
- Multimodal phenotypic classification of generalized anxiety and panic using structural MRI data and psychosocial factors: machine learning results from the German National Cohort (NAKO) study.Translational psychiatry · 2026Article
- Network analysis of childhood trauma and meaning in life in adolescents with and without depression.BMC psychology · 2026Article
- How Childhood Maltreatment Contributes to Explaining Depressive Symptoms in Transgender and Gender-Diverse Individuals.Healthcare (Basel, Switzerland) · 2026Article
- Sex-dependent associations of childhood maltreatment with obesity-related traits: results from the German National Cohort (NAKO).International journal of obesity (2005) · 2026Article
- Kidstime workshops: the evaluation of a multi-family intervention for children of parents with mental illness.European child & adolescent psychiatry · 2026Article
- Exploring intergenerational risk factors and mediators for child abuse potential in high-risk parents of young children.Frontiers in pediatrics · 2026Article
- The vulnerable role of empathy in children who live in conflict zones.European journal of psychotraumatology · 2025Article
- Childhood maltreatment and adult diseases in the general population: the mediating role of smoking and overweight in a time-sequence design.BMC public health · 2025Article
- Childhood trauma and mental health outcomes in Post-COVID Syndrome: Results from a cross-sectional study in Germany.Brain, behavior, & immunity - health · 2025Article
- The association between adverse childhood experiences and chronic respiratory diseases in the Chinese middle-aged and elderly population.BMC public health · 2025Article
- Mechanisms of childhood trauma: an integrative review of a multimodal, transdiagnostic pathway.Neurobiology of stress · 2025Review
- Long-term alteration of heart rate variability following childhood maltreatment: Results of a general population study.European psychiatry : the journal of the Association of European Psychiatrists · 2025Article
- Maternal child maltreatment and trajectories of offspring behavioural and emotional difficulties from age 4 to 7 years - results from a prospective birth cohort study.European child & adolescent psychiatry · 2025Article
- Child Maltreatment Characteristics and Adult Physical Multimorbidity in Germany.JAMA network open · 2025Article
- Effects of multiple stress events at different stages of life on the incidence of metabolic syndrome.Frontiers in endocrinology · 2024Article
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Authors and funding
36 authors at 1 institution in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundChildhood trauma is associated with somatic and mental illness in adulthood. The strength of the association varies as a function of age, sex, and type of trauma. Pertinent studies to date have mainly focused on individual diseases. In this study, we investigate the association between childhood trauma and a multiplicity of somatic and mental illnesses in adulthood.
methodsData from 156 807 NAKO Health Study participants were analyzed by means of logistic regressions, with adjustment for age, sex, years of education, and study site. The Childhood Trauma Screener differentiated between no/minor (n = 115 891) and moderate/severe childhood trauma (n = 40 916). The outcome variables were medical diagnoses of five somatic and two mental health conditions as stated in the clinical history.
resultsPersons with childhood trauma were more likely to bear a diagnosis of all of the studied conditions: cancer (odds ratio [OR] = 1.10; 95% confidence interval: [1.05; 1.15]), myocardial infarction (OR = 1.13 [1.03; 1.24]), diabetes (OR = 1.16, [1.10; 1.23]), stroke (OR = 1.35 [1.23; 1.48]), chronic obstructive pulmonary disease (OR = 1.45 [1.38; 1.52]), depression (OR = 2.36 [2.29; 2.43]), and anxiety disorders (OR = 2.08 [2.00; 2.17]). All of these associations were stronger in younger persons, regardless of the nature of childhood trauma. Differences between the sexes were observed only for some of these associations.
conclusionChildhood trauma was associated with a higher probability of developing mental as well as somatic illness in adulthood. As childhood trauma is an element of individual history that the victim has little to no control over, and because the illnesses that can arise in adulthood in association with it are a heavy burden on the affected persons and on society, there is a need for research on these associations and for the development of preventive measures.
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