Evidence map›Paper›PMID 37876295›Full record

ArticleDeutsches Arzteblatt international2024

Childhood Trauma and Somatic and Mental Illness in Adulthood.

Johanna Klinger-König, Angelika Erhardt, Fabian Streit, Maja P Völker, Matthias B Schulze, Thomas Keil, Julia Fricke, Stefanie Castell, Carolina J Klett-Tammen, Tobias Pischon and 26 more

Open access · greenAbstract read
In one paragraph

Article in Deutsches Arzteblatt international, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
6.0field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 19 citations in OpenAlex.

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  13. Long-term alteration of heart rate variability following childhood maltreatment: Results of a general population study.European psychiatry : the journal of the Association of European Psychiatrists · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

36 authors at 1 institution in 1 country.

Johanna Klinger-KönigDepartment of Psychiatry and Psychotherapy, University Medicine Greifswald, Greifswald, Germany; Institute of Epidemiology and Social Medicine, University of Münster, Münster, Germany; German Center for Neuro degenerative Diseases (DZNE), Site Rostock/Greifswald, Greifswald, Germany; Additional authors have contributed to this publication. They are listed under "cite this as" and at the end of this article together with their affiliations.
Angelika Erhardt
Fabian Streit
Maja P Völker
Matthias B Schulze
Thomas Keil
Julia Fricke
Stefanie Castell
Carolina J Klett-Tammen
Tobias Pischon
André Karch
Henning Teismann
Karin B Michels
K Halina Greiser
Heiko Becher
Stefan Karrasch
Wolfgang Ahrens
Claudia Meinke-Franze
Sabine Schipf
Rafael Mikolajczyk
Amand Führer
Berit Brandes
Börge Schmidt
Carina Emmel
Michael Leitzmann
Julian Konzok
Anette Peters
Nadia Obi
Hermann Brenner
Bernd Holleczek
Ilais Moreno Velásquez
Jürgen Deckert
Bernhard T Baune
Marcella Rietschel
Klaus Berger
Hans J Grabe
Universitätsmedizin Greifswald · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundChildhood trauma is associated with somatic and mental illness in adulthood. The strength of the association varies as a function of age, sex, and type of trauma. Pertinent studies to date have mainly focused on individual diseases. In this study, we investigate the association between childhood trauma and a multiplicity of somatic and mental illnesses in adulthood.

methodsData from 156 807 NAKO Health Study participants were analyzed by means of logistic regressions, with adjustment for age, sex, years of education, and study site. The Childhood Trauma Screener differentiated between no/minor (n = 115 891) and moderate/severe childhood trauma (n = 40 916). The outcome variables were medical diagnoses of five somatic and two mental health conditions as stated in the clinical history.

resultsPersons with childhood trauma were more likely to bear a diagnosis of all of the studied conditions: cancer (odds ratio [OR] = 1.10; 95% confidence interval: [1.05; 1.15]), myocardial infarction (OR = 1.13 [1.03; 1.24]), diabetes (OR = 1.16, [1.10; 1.23]), stroke (OR = 1.35 [1.23; 1.48]), chronic obstructive pulmonary disease (OR = 1.45 [1.38; 1.52]), depression (OR = 2.36 [2.29; 2.43]), and anxiety disorders (OR = 2.08 [2.00; 2.17]). All of these associations were stronger in younger persons, regardless of the nature of childhood trauma. Differences between the sexes were observed only for some of these associations.

conclusionChildhood trauma was associated with a higher probability of developing mental as well as somatic illness in adulthood. As childhood trauma is an element of individual history that the victim has little to no control over, and because the illnesses that can arise in adulthood in association with it are a heavy burden on the affected persons and on society, there is a need for research on these associations and for the development of preventive measures.

Indexed as

Adverse Childhood ExperiencesDiabetes MellitusMental DisordersAnxiety DisordersHumans

Identifiers

PMID37876295
PMCPMC10916765
OpenAlexW4387930877

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.