Evidence map›Paper›PMID 37876008›Full record

ReviewParasites & vectors2023

Insights into the diagnosis, vaccines, and control of Taenia solium, a zoonotic, neglected parasite.

Md Shahadat Hossain, Shafqat Shabir, Philip Toye, Lian F Thomas, Franco H Falcone

Open access · goldAbstract readReview
In one paragraph

Review in Parasites & vectors, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
5.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.

  1. Pooled it
  2. TPx Protein ofPathogens (Basel, Switzerland) · 2026
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  3. The TPx Protein ofCells · 2026
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  12. Use of agricultural waste for optimization of protease production by Pleurotus djamor and evaluation of its anthelmintic activity.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 4 countries.

Md Shahadat HossainDepartment of Parasitology, Bangladesh Agricultural University, Mymensingh, Bangladesh.
Shafqat ShabirInstitute of Parasitology, Justus Liebig University Giessen, Giessen, Germany.
Philip ToyeInternational Livestock Research Institute, Nairobi, Kenya.
Lian F ThomasInternational Livestock Research Institute, Nairobi, Kenya.
Franco H FalconeInstitute of Parasitology, Justus Liebig University Giessen, Giessen, Germany. Franco.Falcone@vetmed.uni-giessen.de.
University of Giessen · DEInternational Livestock Research Institute · KEUniversity of Liverpool · GB

Funding

Bundesministerium für Wirtschaftliche Zusammenarbeit und Entwicklung OHRECA
6 · The paper itself

Abstract

Taenia solium taeniasis/cysticercosis (TSTC) is a foodborne, zoonotic neglected tropical disease affecting predominately low- and middle-income countries. Humans are definitive hosts for T. solium, whereas pigs act as intermediate hosts. Taeniasis, i.e. intestinal infection with adult T. solium in the human host, occurs through ingestion of undercooked pork infected with the larval stage (porcine cysticercosis, PCC). Human cysticercosis occurs after humans ingest T. solium eggs, acting as accidental intermediate hosts. Migration of cysticerci to the human brain results in neurocysticercosis (NCC), manifesting in a variety of clinical symptoms, most notably epilepsy. NCC is the leading cause of acquired epilepsy cases in endemic areas. PCC results in reduced pork value because of condemnation or the risk of condemnation of the meat. Available serological diagnostic tests for porcine and human cysticercosis are characterized by low sensitivity and are not cost-effective. An effective vaccine for T. solium cysticercosis in pigs has been developed, although it is not yet commercially available in all endemic countries, and still no vaccine is available for use in humans. This primer highlights the recent development in the field of diagnostic tests and vaccine production and explores possible strategies for future control and eradication of T. solium. In the absence of highly specific diagnostic tests and human vaccines, treatment of infected pigs and tapeworm carriers and prevention of disease transmission remain the principal means to interrupt the zoonotic cycle of T. solium in endemic countries.

Indexed as

CysticercosisEpilepsyFoodborne DiseasesNeurocysticercosisParasitesSwine DiseasesTaeniasisTaenia soliumVaccinesAdultAnimalsHumansNeglected DiseasesSwineVaccinesDiagnosisHumanNeurocysticercosisPigPorcine cysticercosisTaeniasisTaenia soliumVaccine

Identifiers

PMID37876008
PMCPMC10594694
OpenAlexW4387904399

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.