Evidence map›Paper›PMID 37875764›Full record

ReviewLangenbeck's archives of surgery2023

Global liver transplantation: emerging trends and ethical challenges.

Angela L Hill, Maryam Khan, Amen Z Kiani, Jessica D Lindemann, Neeta Vachharajani, Majella B Doyle, William C Chapman, Adeel S Khan

Abstract readReview
PubMed Publisher
In one paragraph

Review in Langenbeck's archives of surgery, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
6.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 20 citations in OpenAlex.

  1. Steatotic liver disease in Latin America: current views and perspectives.Nature reviews. Gastroenterology & hepatology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Angela L HillWashington University in St. Louis, 660 South Euclid Avenue, Box 8109, St. Louis, MO, 63110, USA.
Maryam KhanCMH Lahore Medical and Dental College, Lahore, Pakistan.
Amen Z KianiWashington University in St. Louis, 660 South Euclid Avenue, Box 8109, St. Louis, MO, 63110, USA.
Jessica D LindemannWashington University in St. Louis, 660 South Euclid Avenue, Box 8109, St. Louis, MO, 63110, USA.
Neeta VachharajaniWashington University in St. Louis, 660 South Euclid Avenue, Box 8109, St. Louis, MO, 63110, USA.
Majella B DoyleWashington University in St. Louis, 660 South Euclid Avenue, Box 8109, St. Louis, MO, 63110, USA.
William C ChapmanWashington University in St. Louis, 660 South Euclid Avenue, Box 8109, St. Louis, MO, 63110, USA.
Adeel S KhanWashington University in St. Louis, 660 South Euclid Avenue, Box 8109, St. Louis, MO, 63110, USA. akhan24@wustl.edu.
Washington University in St. Louis · USCMH Lahore Medical College and Institute of Dentistry · PK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeLiver transplant (LT) is the only definitive treatment for end-stage liver disease (ESLD). This review aims to explore current global LT practices, with an emphasis on challenges and disparities that limit access to LT in different regions of the world.

methodsA detailed analysis was performed of present-day liver transplant practices throughout the world, including the etiology of liver disease, patient access to transplantation, surgical costs, and ongoing ethical concerns.

resultsAnnually, only 10% of the patients needing a liver transplant receive an organ. Currently, the USA performs the highest volume of liver transplants worldwide, followed by China and Brazil. In both North America and Europe, nonalcoholic fatty liver disease is becoming the most common indication for LT, compared to hepatitis B and C in most Asian, South American, and African countries. While deceased donor liver transplant remains the most performed type of LT, living donor liver transplant is becoming increasingly popular in some parts of the world where it is often the only option due to a lack of well-developed infrastructure for deceased organ donation. Ethical concerns in liver transplantation fundamentally revolve around the definition of a deceased donor and the exploitation of living donor liver donation systems.

conclusionGlobally, liver transplant practices and outcomes are varied, with differences driven by healthcare policies, inequities in healthcare access, and ethical concerns.

Indexed as

Hepatitis BLiver TransplantationTissue and Organ ProcurementHumansLiving DonorsWaiting ListsDonor ethicsGlobal surgeryLiver transplantOrgan allocationTransplant access

Identifiers

PMID37875764
OpenAlexW4387930601

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.