ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2023
Stable Decoding from a Speech BCI Enables Control for an Individual with ALS without Recalibration for 3 Months.
Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
37 citing papers in PubMed, 1 synthesis or guideline pooled it, 81 citations in OpenAlex.
- Toward the Clinical Translation of Implantable Brain-Computer Interfaces for Motor Impairment: Research Trends and Outcome Measures.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Pooled it
- Real-time detection of spoken speech from unlabeled ECoG signals: a pilot study with an ALS participant.Journal of neural engineering · 2025Trial
- Speech motor cortex enables BCI cursor control and click.Journal of neural engineering · 2025Trial
- Human learning of noninvasive brain-computer interfaces via manifold geometry.Nature neuroscience · 2026Article
- Simultaneous speech and gesture decoding for multimodal communication in paralysis.Nature neuroscience · 2026Article
- Optimal Size of Electrocorticography Grids for Classification of Hand Movements.Neuroinformatics · 2026Article
- Brain-Computer Interfaces: The Dawn of a New Era in Disease Treatment.Exploration (Beijing, China) · 2026Review
- Electrocorticography During Deep Brain Stimulation Surgery for Movement Disorders: Single-Center Experience.Brain sciences · 2026Article
- Stable speech BCI performance during slow progression of ALS: A longitudinal ECoG study.Research square · 2026Article
- Current status and future prospects of brain-computer interfaces in the field of neurological disease rehabilitation.Frontiers in rehabilitation sciences · 2026Review
- Real-time decoding of full-spectrum Chinese using brain-computer interface.Science advances · 2025Article
- Longitudinal study of gesture decoding in a clinical trial participant with ALS.medRxiv : the preprint server for health sciences · 2025Article
- Transfer learning via distributed brain recordings enables reliable speech decoding.Nature communications · 2025Article
- Progress, challenges and future of linguistic neural decoding with deep learning.Communications biology · 2025Review
- Don't put words in my mouth: speech perception can falsely activate a brain-computer interface.Journal of neuroengineering and rehabilitation · 2025Article
- Implications of shared motor and perceptual activations on the sensorimotor cortex for neuroprosthetic decoding.Journal of neural engineering · 2025Article
- High-gamma electrocorticography activity represents perceived vibration intensity in human somatosensory cortex.medRxiv : the preprint server for health sciences · 2025Article
- 5-year follow-up of a fully implanted brain-computer interface in a spinal cord injury patient.Journal of neural engineering · 2025Article
- Recent applications of EEG-based brain-computer-interface in the medical field.Military Medical Research · 2025Review
- Invasive Brain-Computer Interface for Communication: A Scoping Review.Brain sciences · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
20 authors at 3 institutions in 2 countries.
Funding
Abstract
Brain-computer interfaces (BCIs) can be used to control assistive devices by patients with neurological disorders like amyotrophic lateral sclerosis (ALS) that limit speech and movement. For assistive control, it is desirable for BCI systems to be accurate and reliable, preferably with minimal setup time. In this study, a participant with severe dysarthria due to ALS operates computer applications with six intuitive speech commands via a chronic electrocorticographic (ECoG) implant over the ventral sensorimotor cortex. Speech commands are accurately detected and decoded (median accuracy: 90.59%) throughout a 3-month study period without model retraining or recalibration. Use of the BCI does not require exogenous timing cues, enabling the participant to issue self-paced commands at will. These results demonstrate that a chronically implanted ECoG-based speech BCI can reliably control assistive devices over long time periods with only initial model training and calibration, supporting the feasibility of unassisted home use.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.