Evidence map›Paper›PMID 37875366›Full record

ArticleZhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences2023

Impact of the transforming growth factor-β pathway on vascular restenosis and its mechanism.

Zhongchen Luo, Xin Li, Lunchang Wang, Chang Shu

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 70% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 0 citations in OpenAlex.

  1. [Dual role and therapeutic potential of TREM2 in atherosclerosis].Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Zhongchen LuoInstitute of Vascular Diseases, Central South University, Changsha 410011. 218211098@csu.edu.cn.
Xin LiInstitute of Vascular Diseases, Central South University, Changsha 410011.
Lunchang WangInstitute of Vascular Diseases, Central South University, Changsha 410011.
Chang ShuInstitute of Vascular Diseases, Central South University, Changsha 410011. shuchang@csu.edu.cn.
Central South University · CN

Funding

the National Natural Science Foundation 82120108005the National Science Fundation for Distinguished Young Scholars 81900423
6 · The paper itself

Abstract

As a crucial regulatory molecule in the context of vascular stenosis, transforming growth factor-β (TGF-β), plays a pivotal role in its initiation and progression. TGF-β, a member of the TGF-β superfamily, can bind to the TGF-β receptor and transduce extracellular to intracellular signals through canonical Smad dependent or noncanonical signaling pathways to regulate cell growth, proliferation, differentiation, and apoptosis. Restenosis remains one of the most challenging problems in cardiac, cerebral, and peripheral vascular disease worldwide. The mechanisms for occurrence and development of restenosis are diverse and complex. The TGF-β pathway exhibits diversity across various cell types. Hence, clarifying the specific roles of TGF-β within different cell types and its precise impact on vascular stenosis provides strategies for future research in the field of stenosis.

Indexed as

Transforming Growth Factor betaVascular DiseasesCell DifferentiationConstriction, PathologicHumansSignal TransductionTransforming Growth Factor beta1Transforming Growth FactorsTransforming Growth Factor betaTransforming Growth Factor beta1Transforming Growth Factorsendothelial-mesenchymal transitioninterstitial cellmesenchymal stem celltransforming growth factor-βvascular restenosisvascular smooth muscle cell

Identifiers

PMID37875366
PMCPMC10930841
OpenAlexW4387931142

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.