ArticleChemical research in toxicology2023
Urinary Excretion of Mercapturic Acids of the Rodent Carcinogen Methyleugenol after a Single Meal of Basil Pesto: A Controlled Exposure Study in Humans.
Kai Nieschalke, Nick Bergau, Sönke Jessel, Albrecht Seidel, Susanne Baldermann, Monika Schreiner, Klaus Abraham, Alfonso Lampen, Bernhard H Monien, Burkhard Kleuser and 2 more
Open access · hybridAbstract read
In one paragraphArticle in Chemical research in toxicology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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0 citing papers in PubMed, 3 citations in OpenAlex.
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4 · The recordCorrections and comments
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5 · Who and what moneyAuthors and funding
12 authors at 4 institutions in 1 country.
Kai NieschalkeDepartment of Nutritional Toxicology, Institute of Nutritional Science, University of Potsdam, 14558 Nuthetal, Germany.
Nick BergauDepartment of Food Safety, German Federal Institute for Risk Assessment (BfR), 10589 Berlin, Germany.
Sönke JesselBiochemical Institute for Environmental Carcinogens, Prof. Dr. Gernot Grimmer-Foundation, 22927 Grosshansdorf, Germany.
Albrecht SeidelBiochemical Institute for Environmental Carcinogens, Prof. Dr. Gernot Grimmer-Foundation, 22927 Grosshansdorf, Germany.
Susanne BaldermannDepartment Plant Quality and Food Security, Leibniz Institute of Vegetable and Ornamental Crops (IGZ), 14979 Grossbeeren, Germany.
Monika SchreinerDepartment Plant Quality and Food Security, Leibniz Institute of Vegetable and Ornamental Crops (IGZ), 14979 Grossbeeren, Germany.
Klaus AbrahamDepartment of Food Safety, German Federal Institute for Risk Assessment (BfR), 10589 Berlin, Germany.
Alfonso LampenDepartment of Food Safety, German Federal Institute for Risk Assessment (BfR), 10589 Berlin, Germany.
Bernhard H MonienDepartment of Food Safety, German Federal Institute for Risk Assessment (BfR), 10589 Berlin, Germany.ORCID 0000-0003-1561-2352 Burkhard KleuserDepartment of Nutritional Toxicology, Institute of Nutritional Science, University of Potsdam, 14558 Nuthetal, Germany.
Hansruedi GlattDepartment of Food Safety, German Federal Institute for Risk Assessment (BfR), 10589 Berlin, Germany.ORCID 0000-0001-6053-0562 Fabian SchumacherDepartment of Nutritional Toxicology, Institute of Nutritional Science, University of Potsdam, 14558 Nuthetal, Germany.ORCID 0000-0001-8703-3275 Federal Institute for Risk Assessment · DEUniversity of Potsdam · DEBiochemisches Institut für Umweltcarcinogene · DELeibniz Institute of Vegetable and Ornamental Crops · DE
Funding
No grant is acknowledged in the PubMed record.
6 · The paper itselfAbstract
Methyleugenol (ME), found in numerous plants and spices, is a rodent carcinogen and is classified as "possibly carcinogenic to humans". The hypothesis of a carcinogenic risk for humans is supported by the observation of ME-derived DNA adducts in almost all human liver and lung samples examined. Therefore, a risk assessment of ME is needed. Unfortunately, biomarkers of exposure for epidemiological studies are not yet available. We hereby present the first detection of
Indexed as
AcetylcysteineOcimum basilicumAnimalsCarcinogensChromatography, LiquidDNA AdductsEugenolHumansRodentiaTandem Mass SpectrometryAcetylcysteineCarcinogensDNA AdductsEugenolmethyleugenol
Identifiers
PMID37875262
PMCPMC10664145
OpenAlexW4387898796
What OpenQuestion holds
Textmetadata
LicenceCC BY
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