ArticleAmerican journal of human genetics2023
Estimating heritability explained by local ancestry and evaluating stratification bias in admixture mapping from summary statistics.
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Article in American journal of human genetics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed.
- Article
- Admixture-informed polygenic risk reporting using the ePRS framework.Nature communications · 2026Article
- The Contributions of Multiple Polygenic Scores in Predicting Liability for Major Depressive Disorder and Its Comorbidity with Alcohol Use Disorder.Behavior genetics · 2026Article
- Interpreting SNP heritability in admixed populations.Genetics · 2025Article
- Genomic landscape of cancer in racially and ethnically diverse populations.Nature reviews. Genetics · 2025Review
- Psychiatric genetics in the diverse landscape of Latin American populations.Nature genetics · 2025Review
- Interpreting SNP heritability in admixed populations.bioRxiv : the preprint server for biology · 2025Article
- Rare variant contribution to the heritability of coronary artery disease.Nature communications · 2024Article
- The goldmine of GWAS summary statistics: a systematic review of methods and tools.BioData mining · 2024Article
- Article
Corrections and comments
- Update of
Authors and funding
19 authors.
Tsz Fung ChanCenter for Genetic Epidemiology, Department of Population and Public Health Sciences, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
Xinyue RuiCenter for Genetic Epidemiology, Department of Population and Public Health Sciences, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
David V ContiCenter for Genetic Epidemiology, Department of Population and Public Health Sciences, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
Myriam FornageBrown Foundation Institute for Molecular Medicine, The University of Texas Health Science Center, Houston, TX, USA.
Mariaelisa GraffDepartment of Epidemiology, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, NC, USA.
Jeffrey HaesslerDivision of Public Health Sciences, Fred Hutchinson Cancer Center, Seattle, WA, USA.
Christopher HaimanCenter for Genetic Epidemiology, Department of Population and Public Health Sciences, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
Heather M HighlandDepartment of Epidemiology, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, NC, USA.
Su Yon JungTranslational Sciences Section, School of Nursing, Jonsson Comprehensive Cancer Center, University of California, Los Angeles, Los Angeles, CA, USA.
Eimear E KennyInstitute for Genomic Health, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Charles KooperbergDivision of Public Health Sciences, Fred Hutchinson Cancer Center, Seattle, WA, USA.
Loic Le MarchandEpidemiology Program, University of Hawaii Cancer Center, Honolulu, HI, USA.
Kari E NorthDepartment of Epidemiology, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, NC, USA.
Ran TaoDepartment of Biostatistics, Vanderbilt University Medical Center, Nashville, TN, USA; Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN, USA.
Genevieve WojcikDepartment of Epidemiology, Bloomberg School of Public Health, John Hopkins University, Baltimore, MD, USA.
Christopher R GignouxColorado Center for Personalized Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.
PAGE Consortium
Charleston W K ChiangCenter for Genetic Epidemiology, Department of Population and Public Health Sciences, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA; Department of Quantitative and Computational Biology, University of Southern California, Los Angeles, CA, USA.
Nicholas MancusoCenter for Genetic Epidemiology, Department of Population and Public Health Sciences, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA; Department of Quantitative and Computational Biology, University of Southern California, Los Angeles, CA, USA. Electronic address: nicholas.mancuso@med.usc.edu.
Funding
Leveraging Prospective Cancer Epidemiology Cohorts and Novel Methods to Improve Polygenic Risk ScoresU01CA261339 · NCI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI Fei Chen, David V Conti · 2021 to 2026
$5.2MCharacterizing the evolutionary architecture of complex disease within and across diverse populationsR01HG012133 · NHGRI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI MANCUSO, NICHOLAS · 2021 to 2025
$3.6MThe influence of genetic ancestry and population-specific epidemiology on the transferability of genomic findings to diverse and admixed populationsR35HG011944 · NHGRI · JOHNS HOPKINS UNIVERSITY · PI WOJCIK, GENEVIEVE LIANNE · 2021 to 2025
$2.3MAn evolutionary framework to elucidate and interpret the genetic architecture of complex traits in diverse populations - diversity supplementR35GM142783 · NIGMS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI CHIANG, CHARLESTON · 2021 to 2025
$2.2MNCI NIH HHS U01 CA261339NHGRI NIH HHS R01 HG012133NHGRI NIH HHS R35 HG011944NIGMS NIH HHS R35 GM142783
Abstract
The heritability explained by local ancestry markers in an admixed population (h
Indexed as
Black or African AmericanGenetics, PopulationChromosome MappingHumansPhenotypePolymorphism, Single Nucleotideadmixture mappingfamily-wise error rategenetic admixturegenome-wide associationheritabilitylocal ancestrypopulation structuresummary statistics
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What OpenQuestion holds
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Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.