Evidence map›Paper›PMID 37874825›Full record

ArticlePloS one2023

The impact of COVID-19 on opioid toxicity deaths for people who experience incarceration compared to the general population in Ontario: A whole population data linkage study.

Amanda Butler, Ruth Croxford, Katherine E McLeod, Tara Gomes, Aaron M Orkin, Susan J Bondy, Fiona G Kouyoumdjian

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.2field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 1 country.

Amanda ButlerSchool of Criminology, Simon Fraser University, Burnaby, British Columbia, Canada.ORCID 0000-0002-9961-4306
Ruth CroxfordFreelance Statistician, Toronto, Ontario, Canada.
Katherine E McLeodDepartment of Family Medicine, McMaster University, Hamilton, Canada.
Tara GomesMAP Centre for Urban Health Solutions, Li Ka Ching Knowledge Institute, St. Michael's Hospital, Toronto, Ontario, Canada.
Aaron M OrkinDepartment of Family and Community Medicine, University of Toronto, Toronto, Ontario, Canada.
Susan J BondyDalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada.
Fiona G KouyoumdjianDepartment of Family Medicine, McMaster University, Hamilton, Canada.
McMaster University · CAUniversity of Toronto · CASimon Fraser University · CAStatistics Canada · CASt. Michael's Hospital · CA

Funding

CIHR SMN-139150
6 · The paper itself

Abstract

backgroundTo inform preparedness and population health action, we need to understand the effects of COVID-19 on health inequities. In this study, we assess the impact of COVID-19 on opioid toxicity deaths among people who experience incarceration compared to others in the general population in Ontario, Canada.

methodsWe conducted a retrospective cohort study for the period of January 1, 2015 to December 31, 2020. We accessed and linked coronial data on all opioid toxicity deaths in Ontario with correctional data for people aged 18 years and older who were incarcerated in a provincial correctional facility. We used data from the Statistics Canada Census to calculate whole population rates. We used an interrupted time series design and segmented regression to assess for change in the level or rate of increase in deaths due to opioid toxicity coinciding with the COVID-19 pandemic. We compared the impact of COVID-19 on the opioid toxicity death rates for people exposed and not exposed to incarceration.

resultsRates of opioid toxicity death increased with a linear positive slope in both persons exposed to incarceration and those not exposed over the study period. The start of COVID-19 measures coincided with a marked upward shift in the trend lines with modification of the effect of COVID-19 by both sex and exposure to incarceration. For persons exposed to incarceration, the risk ratio (RR) was 1.50 (95%CI 1.35-1.69) for males and 1.21 (95%CI 1.06-1.42) for females, and for persons not exposed to incarceration, the RR was 1.25 (95%CI 1.13-1.38) for males and not significant for females.

conclusionsCOVID-19 substantially exacerbated the risk of opioid toxicity death, impacting males and females who experienced incarceration more than those who had not, with an immediate stepwise increase in risk but no change in the rate of increase of risk over time. Public health work, including pandemic preparedness, should consider the specific needs and circumstances of people who experience incarceration.

Indexed as

COVID-19Opioid-Related DisordersPrisonersAnalgesics, OpioidCorrectional FacilitiesFemaleHumansMaleOntarioPandemicsRetrospective StudiesAnalgesics, Opioid

Identifiers

PMID37874825
PMCPMC10597506
OpenAlexW4387909681

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.