Evidence map›Paper›PMID 37874478›Full record

ArticleCancer causes & control : CCC2024

Racial and socioeconomic disparities in survival among women with advanced-stage ovarian cancer who received systemic therapy.

Caretia J Washington, Shama D Karanth, Meghann Wheeler, Livingstone Aduse-Poku, Dejana Braithwaite, Tomi F Akinyemiju

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cancer causes & control : CCC, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Global, regional, and national burden of ovarian cancer among young women during 1990-2019.European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP) · 2025
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Caretia J Washington *Department of Epidemiology, University of Florida College of Public Health and Health Professions, Gainesville, FL, USA.
Shama D Karanth *University of Florida Health Cancer Center, Gainesville, FL, USA.
Meghann WheelerDepartment of Epidemiology, University of Florida College of Public Health and Health Professions, Gainesville, FL, USA.
Livingstone Aduse-PokuDepartment of Epidemiology, University of Florida College of Public Health and Health Professions, Gainesville, FL, USA.
Dejana BraithwaiteDepartment of Epidemiology, University of Florida College of Public Health and Health Professions, Gainesville, FL, USA.
Tomi F AkinyemijuDepartment of Population Health Sciences, Duke University School of Medicine, Durham, NC, 27708, USA. tomi.akinyemiju@duke.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe purpose of this study was to assess the association between race/ethnicity and all-cause mortality among women with advanced-stage ovarian cancer who received systemic therapy.

methodsWe analyzed data from the National Cancer Database on women diagnosed with advanced-stage ovarian cancer from 2004 to 2015 who received systemic therapy. Race/ethnicity was categorized as Non-Hispanic (NH) White, NH-Black, Hispanic, NH-Asian/Pacific Islander, and Other. Income and education were combined to form a composite measure of socioeconomic status (SES) and categorized into low-, mid-, and high-SES. Multivariable Cox proportional hazards models were used to assess whether race/ethnicity was associated with the risk of death after adjusting for sociodemographic, clinical, and treatment factors. Additionally, subgroup analyses were conducted by SES, age, and surgery receipt.

resultsThe study population comprised 53,367 women (52.4% ages ≥ 65 years, 82% NH-White, 8.7% NH-Black, 5.7% Hispanic, and 2.7% NH-Asian/Pacific Islander) in the analysis. After adjusting for covariates, the NH-Black race was associated with a higher risk of death versus NH-White race (aHR: 1.12; 95% CI: 1.07,1.18), while Hispanic ethnicity was associated with a lower risk of death compared to NH-White women (aHR: 0.87; 95% CI: 0.80, 0.95). Furthermore, NH-Black women versus NH-White women had an increased risk of mortality among those with low-SES characteristics (aHR:1.12; 95% CI:1.03-1.22) and mid-SES groups (aHR: 1.13; 95% CI:1.05-1.21).

conclusionsAmong women with advanced-stage ovarian cancer who received systemic therapy, NH-Black women experienced poorer survival compared to NH-White women. Future studies should be directed to identify drivers of ovarian cancer disparities, particularly racial differences in treatment response and surveillance.

Indexed as

Carcinoma, Ovarian EpithelialOvarian NeoplasmsSocial Determinants of HealthSocioeconomic Disparities in HealthAsian American Native Hawaiian and Pacific IslanderBlack or African AmericanEthnicityFemaleHispanic or LatinoHumansWhite PeopleCancer disparitiesGynecologic cancersSocioeconomic statusSystemic therapy

Identifiers

PMID37874478
PMCPMC10838826

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.