Evidence map›Paper›PMID 37874390›Full record

ArticleWorld journal of microbiology & biotechnology2023

Campylobacter jejuni and Campylobacter coli in human stool samples: antibiotic resistance profiles, putative virulence determinants and molecular characterization of the isolates.

Harun Hizlisoy, Pinar Sagiroglu, Mukaddes Barel, Adalet Dishan, Candan Gungor, Kursat Koskeroglu, Serhat Hizlisoy, Mustafa Altay Atalay

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Article in World journal of microbiology & biotechnology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Review
  5. Diagnosis ofIndian journal of microbiology · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Harun HizlisoyDepartment of Veterinary Public Health, Faculty of Veterinary Medicine, Erciyes University, Kayseri, Turkey. hizlisoy@erciyes.edu.tr.
Pinar SagirogluDepartment of Medical Microbiology, Faculty of Medicine, Erciyes University, Kayseri, Turkey.
Mukaddes BarelDepartment of Veterinary Public Health, Faculty of Veterinary Medicine, Erciyes University, Kayseri, Turkey.
Adalet DishanDepartment of Food Hygiene and Technology, Faculty of Veterinary Medicine, Yozgat Bozok University, Sorgun, Yozgat, Turkey.
Candan GungorDepartment of Veterinary Public Health, Faculty of Veterinary Medicine, Erciyes University, Kayseri, Turkey.
Kursat KoskerogluDepartment of Veterinary Public Health, Faculty of Veterinary Medicine, Erciyes University, Kayseri, Turkey.
Serhat HizlisoyDepartment of Computer Engineering, Faculty of Engineering and Architecture, Kayseri University, Kayseri, Turkey.
Mustafa Altay AtalayDepartment of Medical Microbiology, Faculty of Medicine, Erciyes University, Kayseri, Turkey.
Erciyes University · TRBozok Universitesi · TRKayseri Üniversitesi

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Campylobacters, especially C. jejuni and C. coli, have become one of the leading causes of acute gastroenteritis in humans worldwide in recent years. We aimed to investigate the presence, antimicrobial resistance, putative virulence genes, and molecular characterization of C. jejuni and C. coli recovered from human acute gastroenteritis cases in the study. In the study, suspected Campylobacter spp. isolates were obtained in 43 (5%) feces samples collected from a total of 850 patients who applied to the Erciyes University Medical Faculty acute clinic between March 2019 and February 2020. As a result of the phenotypic tests, these isolates were determined to be Campylobacter spp. According to the multiplex PCR, 33 of 43 Campylobacter spp. isolates were identified as C. jejuni (76%) and ten isolates were as C. coli (24%). In the disc diffusion test, the highest resistance rate was found in the trimethoprim/sulfamethoxazole (90.1%) and ciprofloxacin (90.1%), and the lowest rate was found in the amoxicillin-clavulanic acid (9.3%). In Campylobacter spp. isolates, the virulence genes cdtA, virB11, cdtB, cadF, iam, ceu, and flaA were found to be positive at rates of 26 (60%), 28 (65.6%), 13 (30%), 4 (9%), 27 (62%), 17 (39%), and 7 (16%), respectively. However, the cdtC gene was not detected in any of the isolates. The study searched tetO gene to examine the genetic aspect of tetracycline resistance, which was found in all Campylobacter spp. isolates. In the PCR reactions to investigate A2074C and A2075G mutations of macrolide resistance, it was determined as 7 (16%) and 21 (48%) of the isolates. To detect quinolone resistance, the rates of quinolone resistance-determining regions (QRDR) were 20 (45.4%) and the gyrA gene mutations in the mismatch amplification mutation assay PCR (MAMA-PCR), were 19 (43.1%) of isolates. In addition, the quinolone resistance gene (qnr) carried by plasmid in Campylobacter isolates was not found in the study. Bla

Indexed as

CampylobacterCampylobacter coliCampylobacter InfectionsCampylobacter jejuniGastroenteritisAnti-Bacterial AgentsCiprofloxacinDrug Resistance, BacterialFecesHumansMacrolidesVirulenceVirulence FactorsAnti-Bacterial AgentsCiprofloxacinMacrolidesVirulence FactorsAcute gastroenteritisCampylobacter spp.HumanMultidrug resistanceVirulence genes

Identifiers

PMID37874390
OpenAlexW4387893785

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.