Evidence map›Paper›PMID 37874357›Full record

ArticlePediatric nephrology (Berlin, Germany)2024

Epidemiology of acute kidney injury in children: a report from the 26th Acute Disease Quality Initiative (ADQI) consensus conference.

Scott M Sutherland, Rashid Alobaidi, Stephen M Gorga, Arpana Iyengar, Catherine Morgan, Emma Heydari, A Ayse Akcan Arikan, Raj K Basu, Stuart L Goldstein, Michael Zappitelli and 1 more

Open access · hybridAbstract readConsensus Statement
In one paragraph

Article in Pediatric nephrology (Berlin, Germany), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Research progress on biomarkers for acute kidney injury in children.Pediatric nephrology (Berlin, Germany) · 2026
    Review
  3. Clinical Profile and Survival Outcomes of Children with Acute Kidney Injury Requiring Renal Replacement Therapy: A Retrospective Study from a Tertiary Pediatric Intensive Care Unit.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2026
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 8 institutions in 3 countries.

Scott M SutherlandDepartment of Pediatrics, Division of Nephrology, Center for Academic Medicine, Stanford University School of Medicine, Palo Alto, CA, USA. suthersm@stanford.edu.
Rashid AlobaidiDepartment of Pediatrics, University of Alberta, Edmonton, AB, Canada.
Stephen M GorgaDepartment of Pediatrics, University of Michigan Medical School, Ann Arbor, MI, USA.
Arpana IyengarDepartment of Paediatric Nephrology, St. John's National Academy of Health Sciences, Bangalore, India.
Catherine MorganDepartment of Pediatrics, University of Alberta, Edmonton, AB, Canada.
Emma HeydariDepartment of Pediatrics, University of Alberta, Edmonton, AB, Canada.
A Ayse Akcan ArikanDepartment of Pediatrics, Section of Critical Care Medicine, Baylor College of Medicine, Texas Children's Hospital, Houston, TX, USA.
Raj K BasuDepartment of Pediatrics, Northwestern University, Chicago, IL, USA.
Stuart L GoldsteinDepartment of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, USA.
Michael ZappitelliDepartment of Pediatrics, Hospital for Sick Children, University of Toronto, Toronto, ON, Canada. michael.zappitelli@sickkids.ca.ORCID 0000-0002-9977-0536
ADQI 26 Workgroup
University of Alberta · CABaylor College of Medicine · USNorthwestern University · USStanford Medicine · USSt. John's National Academy of Health Sciences · INUniversity of Cincinnati Medical Center · USUniversity of Michigan · USUniversity of Toronto · CA

Funding

Developing a Precision Medicine Approach to Pediatric Sepsis-Associated Acute Kidney Injury: Identification of Unique Subphenotypes and Strategies for Bedside ImplementationK23GM151444 · NIGMS · CINCINNATI CHILDRENS HOSP MED CTR · PI Natalja L. Stanski · 2023 to 2026
$769k
NIGMS NIH HHS K23 GM151444
6 · The paper itself

Abstract

The nephrology and critical care communities have seen an increase in studies exploring acute kidney injury (AKI) epidemiology in children. As a result, we now know that AKI is highly prevalent in critically ill neonates, children, and young adults. Furthermore, children who develop AKI experience greater morbidity and higher mortality. Yet knowledge gaps still exist that suggest a more comprehensive understanding of AKI will form the foundation for future efforts designed to improve outcomes. In particular, the areas of community acquired AKI, AKI in non-critically ill children, and cohorts from low-middle income countries have not been well studied. Longer-term functional outcomes and patient-centric metrics including social determinants of health, quality of life, and healthcare utilization should be the foci of the next phase of scholarship. Current definitions identify AKI-based upon evidence of dysfunction which serves as a proxy for injury; biomarkers capable of identifying injury as it occurs are likely to more accurately define populations with AKI. Despite the strength of the association, the causal and mechanistic relationships between AKI and poorer outcomes remain inadequately examined. A more robust understanding of the relationship represents a potential to identify therapeutic targets. Once established, a more comprehensive understanding of AKI epidemiology in children will allow investigation of preventive, therapeutic, and quality improvement interventions more effectively.

Indexed as

Acute Kidney InjuryQuality of LifeAcute DiseaseChildHumansInfant, NewbornRisk FactorsAcute kidney injuryADQIAKI epidemiology

Identifiers

PMID37874357
PMCPMC10817829
OpenAlexW4387893457

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.