Evidence map›Paper›PMID 37873913›Full record

ArticleCurrent computer-aided drug design2024

Amul S Bahl, Vipin Kumar Verma, Vaishali Prajapati, Jagriti Bhatia, Dharamvir Singh Arya

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Article in Current computer-aided drug design, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Amul S BahlDepartment of Research, Development and Innovation, God's Own Store LLP, New Delhi, 110065, India.
Vipin Kumar VermaDeptartment of Pharmacology, All India Institute of Medical Sciences, New Delhi, 110029, India.ORCID 0000-0003-0664-087X
Vaishali PrajapatiDeptartment of Pharmacology, All India Institute of Medical Sciences, New Delhi, 110029, India.
Jagriti BhatiaDeptartment of Pharmacology, All India Institute of Medical Sciences, New Delhi, 110029, India.
Dharamvir Singh AryaDeptartment of Pharmacology, All India Institute of Medical Sciences, New Delhi, 110029, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDiabetes mellitus (DM) is characterized by elevated blood glucose levels either due to insufficient insulin production, defective insulin action, or both. It affects nearly 537 million individuals worldwide. Pharmacological treatment involves the use of oral antidiabetic agents as mono or combination therapy that effectively aids in controlling hyperglycemia. Despite providing therapeutic benefits, these medications limit their use owing to adverse side effects. Certain natural products, including essential oils, have promising anti-diabetic properties.

objectiveThe present study explores the effectiveness of two polyherbal oils and their compound towards the treatment of DM based on an

resultsThe compounds identified through GC-MS analysis possess anti-diabetic and antiinflammatory properties. With the aid of

conclusionOur data suggest an agonistic effect of compounds on target proteins aiding in enhanced insulin activity and could serve as a potential anti-diabetic agent.

Indexed as

Computer SimulationHypoglycemic AgentsMolecular Docking SimulationDiabetes MellitusGas Chromatography-Mass SpectrometryHumansMolecular Dynamics SimulationOils, VolatilePlant OilsHypoglycemic AgentsOils, VolatilePlant Oilsanti-diabeticsgas chromatography-mass spectrometryimpaired glucose tolerance.molecular dynamics simulationsPolyherbal oilprotein-ligand docking

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.