Evidence map›Paper›PMID 37873787›Full record

ArticleDiseases (Basel, Switzerland)2023

Cold Anaphylaxis in Children: Italian Case Series and Review of the Literature.

Leonardo Tomei, Francesca Saretta, Stefania Arasi, Lucrezia Sarti, Amelia Licari, Mattia Giovannini, Simona Barni, Giulia Liccioli, Valeria Tallarico, Alessandra Piccorossi and 3 more

Open access · goldAbstract read
In one paragraph

Article in Diseases (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 4 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 7 institutions in 1 country.

Leonardo TomeiAllergy Unit, Meyer Children's Hospital IRCCS, 50139 Florence, Italy.ORCID 0000-0002-7177-7939
Francesca SarettaPediatric Department, Latisana-Palmanova Hospital, Azienda Sanitaria Universitaria Friuli Centrale, 33100 Udine, Italy.ORCID 0000-0001-9443-5483
Stefania ArasiTranslational Research in Pediatric Specialties Area, Division of Allergy, Bambino Gesù Children's Hospital IRCCS, 00165 Rome, Italy.ORCID 0000-0002-8135-0568
Lucrezia SartiAllergy Unit, Meyer Children's Hospital IRCCS, 50139 Florence, Italy.
Amelia LicariPediatric Clinic, Fondazione IRCCS Policlinico San Matteo, University of Pavia, 27100 Pavia, Italy.ORCID 0000-0002-1773-6482
Mattia GiovanniniAllergy Unit, Meyer Children's Hospital IRCCS, 50139 Florence, Italy.ORCID 0000-0001-9568-6882
Simona BarniAllergy Unit, Meyer Children's Hospital IRCCS, 50139 Florence, Italy.ORCID 0000-0001-5598-2740
Giulia LiccioliAllergy Unit, Meyer Children's Hospital IRCCS, 50139 Florence, Italy.
Valeria TallaricoPediatric Unit, University Hospital Renato Dulbecco, 88100 Catanzaro, Italy.ORCID 0009-0000-1575-1905
Alessandra PiccorossiPediatric Unit, Bufalini Hospital, AUSL Romagna, 47521 Cesena, Italy.
Carlo CaffarelliPediatric Clinic, Medicine and Surgery Department, Azienda Ospedaliero-Universitaria, University of Parma, 43126 Parma, Italy.ORCID 0000-0001-7710-6995
Elio NovembreDepartment of Health Sciences, University of Florence, 50139 Florence, Italy.
Francesca MoriAllergy Unit, Meyer Children's Hospital IRCCS, 50139 Florence, Italy.
Meyer Children's Hospital · ITBambino Gesù Children's Hospital · ITOspedale di Latisana · ITOspedale “M. Bufalini” di Cesena · ITUniversity of Florence · ITUniversity of Parma · ITUniversity of Pavia · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chronic urticaria (CU) is one of the most common skin disorders worldwide. Among the inducible subgroup of CU, cold urticaria (ColdU) can affect both children and adults and is the only type associated with the risk of anaphylaxis without cofactors. In the scientific literature, data about cold anaphylaxis (ColdA) are poor, especially at pediatric age, and little is known about risk factors associated with the onset of systemic reactions and about the criteria for prescribing adrenaline auto-injectors (AAIs) in these patients. We describe the clinical characteristics and management of a case series of 21 patients with a history of ColdA, and we compare them with the pediatric case reports and case series published so far. On the basis of the scientific literature and of our case series of patients, we suggest that AAI should be prescribed to all high-risk patients: those with urticaria caused by cold-water immersion, oropharyngeal reactions, and with a previous history of systemic symptoms or anaphylaxis.

Indexed as

anaphylaxischronic urticariacold urticariapediatrics

Identifiers

PMID37873787
PMCPMC10594430
OpenAlexW4387744100

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.