Evidence map›Paper›PMID 37873767›Full record

ArticleThe Journal of international medical research2023

HHV-6B- and HHV-7-associated choroiditis secondary to acute myelogenous leukemia: a case report.

Jing Xu, Linjiang Chen, Tao Cen, Yuanping Zeng, Qiong Liu

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of international medical research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Jing XuDepartment of Ophthalmology, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong, China.ORCID 0000-0002-8000-2510
Linjiang ChenDepartment of Ophthalmology, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong, China.
Tao CenDepartment of Research and Development, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong, China.
Yuanping ZengDepartment of Ophthalmology, Baiyun Branch, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong, China.
Qiong LiuDepartment of Ophthalmology, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong, China.
Nanfang Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report a case of human herpes virus 6 (HHV-6)- and human herpes virus 7 (HHV-7)-associated choroiditis in an immunocompromised woman. A 42-year-old Chinese woman with a history of acute myelogenous leukemia presented with blurred vision and black floaters in her right eye. Anterior segment examination findings were normal. Ophthalmoscopic examination revealed a subretinal lesion in the superonasal peripapillary region with several punctate hemorrhages. Optical coherence tomography showed a crater-like choroidal protuberance, associated with retinal pigment epithelium rupture and full-thickness retinal edema in the involved area. Indocyanine green angiography demonstrated a broad hypofluorescent lesion in the choroid. The patient was diagnosed with choroiditis. Subsequently, metagenomic next-generation sequencing revealed HHV-6B and HHV-7 DNA in the aqueous humor. Therefore, antiviral therapy was initiated. The patient experienced resolution of all symptoms and signs after treatment with intravenous foscarnet and oral acyclovir. The findings in this case indicate that HHV-6 and HHV-7 can cause ocular infection, particularly in immunocompromised patients.

Indexed as

ChoroiditisHerpesvirus 6, HumanHerpesvirus 7, HumanLeukemia, Myeloid, AcuteAdultChoroidFemaleHumansTomography, Optical Coherencecase reportchoroiditisHuman herpesvirus-6human herpesvirus-7immunocompromised hostmetagenomic next-generation sequencing

Identifiers

PMID37873767
PMCPMC10594963
OpenAlexW4387892918

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.