Evidence map›Paper›PMID 37873749›Full record

ArticleMedical sciences (Basel, Switzerland)2023

May Nutritional Status Positively Affect Disease Progression and Prognosis in Patients with Esophageal and Pharyngeal Cancers? A Scoping Review of the Current Clinical Studies.

Georgios Antasouras, Sousana K Papadopoulou, Maria Tolia, Aimilia-Lynn Pandi, Maria Spanoudaki, Nikolaos Tsoukalas, Gerasimos Tsourouflis, Evmorfia Psara, Maria Mentzelou, Constantinos Giaginis

Open access · goldAbstract readScoping Review
In one paragraph

Article in Medical sciences (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
4.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 1 country.

Georgios AntasourasDepartment of Food Science and Nutrition, School of the Environment, University of the Aegean, 81400 Lemnos, Greece.
Sousana K PapadopoulouDepartment of Nutritional Sciences and Dietetics, Faculty of Health Sciences, International Hellenic University, 57400 Thessaloniki, Greece.ORCID 0000-0002-6408-6128
Maria ToliaDepartment of Radiotherapy, Faculty of Medicine, School of Health Sciences, University of Crete, 71110 Heraklion, Crete, Greece.ORCID 0000-0001-5822-4363
Aimilia-Lynn PandiDepartment of Food Science and Nutrition, School of the Environment, University of the Aegean, 81400 Lemnos, Greece.
Maria SpanoudakiDepartment of Nutritional Sciences and Dietetics, Faculty of Health Sciences, International Hellenic University, 57400 Thessaloniki, Greece.
Nikolaos TsoukalasDepartment of Oncology, 401 General Army Hospital of Athens (401 Geniko Stratiotiko Nosokomeio Athenon), 11525 Athens, Greece.ORCID 0000-0002-1455-1503
Gerasimos TsourouflisSecond Department of Propedeutic Surgery, Medical School, University of Athens, 11527 Athens, Greece.
Evmorfia PsaraDepartment of Food Science and Nutrition, School of the Environment, University of the Aegean, 81400 Lemnos, Greece.
Maria MentzelouDepartment of Food Science and Nutrition, School of the Environment, University of the Aegean, 81400 Lemnos, Greece.
Constantinos GiaginisDepartment of Food Science and Nutrition, School of the Environment, University of the Aegean, 81400 Lemnos, Greece.ORCID 0000-0003-2878-4831
University of the Aegean · GRInternational Hellenic University · GR401 General Military Hospital of Athens · GRNational and Kapodistrian University of Athens · GRUniversity of Crete · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMalnutrition in esophageal and pharyngeal cancer patients constitutes a common and serious concern, which significantly reduces patients' prognoses. Cancers of the esophagus and the pharynx can considerably impair feeding in patients, resulting in severe undernutrition. This is a scoping review that intends to critically analyze the most well-designed clinical studies investigating the potential beneficial impact of diverse nutritional assessment tools on the prognosis of patients with esophageal and pharyngeal cancers.

methodsThe most accurate and remarkable scientific databases were comprehensively explored utilizing relative keywords to detect clinical studies that investigate whether nutritional status may affect disease prognosis.

resultsSeveral assessment tools have evaluated and highlighted the potential beneficial impact of nutritional status on disease progression and patients' prognosis in both esophageal and pharyngeal cancers. Regarding esophageal cancer, CONUT, PNI, PG-SGA, and NRS-2002 are more commonly used, while albumin is also frequently evaluated. Regarding pharyngeal cancers, fewer studies are currently available. PNI has been evaluated, and its significance as a factor for shorter survival' times has been highlighted. The Comprehensive Nutritional Index has also been evaluated with positive results, as well as NRS 2002, GPS, and body-weight status. However, there is currently a lack of studies with an adequate number of women with cancer. An international literature gap was identified concerning follow-up studies with adequate methodology.

conclusionsNutritional status may significantly affect disease progression and patients' survival, highlighting the significance of a great nutritional status in individuals with esophageal and pharyngeal cancers. Further large-scale and well-designed prospective surveys should be performed to verify the potential beneficial effects of adequate nourishment in people suffering from cancer of the esophagus and pharynx.

Indexed as

Esophageal NeoplasmsPharyngeal NeoplasmsDisease ProgressionFemaleHumansNutritional StatusPrognosisProspective Studieschemotherapydiagnosisesophageal cancermalnutritionnutritional assessmentnutritional statuspharyngeal cancerprognosisradiotherapysurvival

Identifiers

PMID37873749
PMCPMC10594480
OpenAlexW4387304303

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.