ArticleHuman brain mapping2023
Association between activity in the ventral premotor cortex and spinal cord activation during force generation-A combined cortico-spinal fMRI study.
Article in Human brain mapping, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 21 citations in OpenAlex.
- Test-Retest Reliability of Sensorimotor Activity Measured With Spinal Cord fMRI.Human brain mapping · 2026Article
- Complexity matching: adaptive strong anticipation enhances motor coordination.Experimental brain research · 2026Article
- Integrated neuroimaging and robotic rehabilitation in chronic stroke: Neural correlates and predictors of motor recovery.Experimental and therapeutic medicine · 2025Article
- Data-driven denoising in spinal cord fMRI with principal component analysis.bioRxiv : the preprint server for biology · 2025Article
- A Virtual Reality Force Control Training System on Brain Activation: Functional Near-Infrared Spectroscopy (fNIRS) Study.JMIR serious games · 2025Article
- Altered Functional Connectivity Between Cortical Premotor Areas and the Spinal Cord in Chronic Stroke.Stroke · 2025Article
- Mapping hand function with simultaneous brain-spinal cord functional MRI.Imaging neuroscience (Cambridge, Mass.) · 2025Article
- A multichannel electrophysiological approach to noninvasively and precisely record human spinal cord activity.PLoS biology · 2024Article
- Functional magnetic resonance imaging of the lumbosacral cord during a lower extremity motor task.Imaging neuroscience (Cambridge, Mass.) · 2024Article
- Cerebro-spinal somatotopic organization uncovered through functional connectivity mapping.Imaging neuroscience (Cambridge, Mass.) · 2024Article
- Recent developments and future avenues for human corticospinal neuroimaging.Frontiers in human neuroscience · 2024Review
- Association between activity in the ventral premotor cortex and spinal cord activation during force generation-A combined cortico-spinal fMRI study.Human brain mapping · 2023Article
- Data-driven denoising in spinal cord fMRI with principal component analysis.Imaging neuroscience (Cambridge, Mass.)Article
Corrections and comments
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
Abstract
Force generation is a crucial element of dexterity and a highly relevant skill of the human motor system. How cerebral and spinal components interact and how spinal activation is associated with the activity in the cerebral primary motor and premotor areas is poorly understood. Here, we conducted combined cortico-spinal functional magnetic resonance imaging during a simple visually guided isometric force generation task in 20 healthy young subjects. Activation was localized in the right cervical spinal cord and left primary motor and premotor areas. The main finding is that spinal activation was negatively correlated with ventral premotor cortex activation. Spinal activation was furthermore significantly correlated with primary motor cortex activation, while increasing target forces led to an increase in the amount of activation. These data indicate that human premotor areas such as the ventral premotor cortex might be functionally connected to the lower cervical spinal cord contributing to distal upper limb functions, a finding that extends our understanding of human motor function beyond the animal literature.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.