Evidence map›Paper›PMID 37873577›Full record

ArticleAmerican journal of physiology. Gastrointestinal and liver physiology2023

Rachel E Hopton, Nicholas J Jahahn, Anne E Zemper

Abstract read
In one paragraph

Article in American journal of physiology. Gastrointestinal and liver physiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Rachel E HoptonInstitute of Molecular Biology, University of Oregon, Eugene, Oregon, United States.ORCID 0000-0002-7450-3378
Nicholas J JahahnInstitute of Molecular Biology, University of Oregon, Eugene, Oregon, United States.
Anne E ZemperDepartment of Biology, University of Oregon, Eugene, Oregon, United States.ORCID 0000-0001-8238-1406

Funding

DEVELOPMENTAL BIOLOGY TRAINING PROGRAMT32HD007348 · NICHD · UNIVERSITY OF OREGON · PI Chris Q Doe, KRYN STANKUNAS · 1989 to 2026
$6.8M
HHS | NIH | Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) T32HD007348NICHD NIH HHS T32 HD007348
6 · The paper itself

Abstract

Growth and specification of the mouse intestine occurs in utero and concludes after birth. Although numerous studies have examined this developmental process in the small intestine, far less is known about the cellular and molecular cues required for colon development. In this study, we examine the morphological events leading to crypt formation, epithelial cell differentiation, proliferation, and the emergence and expression of a stem and progenitor cell marker Lrig1. Through multicolor lineage tracing, we show Lrig1-expressing cells are present at birth and behave as stem cells to establish clonal crypts within 3 wk of life. In addition, we use an inducible knockout mouse to eliminate

Indexed as

Colonic NeoplasmsNerve Tissue ProteinsAnimalsCell ProliferationColonIntestinal MucosaIntestine, SmallMembrane GlycoproteinsMiceMice, KnockoutLrig1 protein, mouseMembrane GlycoproteinsNerve Tissue ProteinscolondevelopmentLrig1stem cells

Identifiers

PMID37873577
PMCPMC11192189

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.