Evidence map›Paper›PMID 37873489›Full record

ArticlebioRxiv : the preprint server for biology2023

Secretory Leukocyte Protease Inhibitor Protects Against Severe Urinary Tract Infection in Mice.

Anne L Rosen, Michael A Lint, Dayne H Voelker, Nicole M Gilbert, Christopher P Tomera, Jesús Santiago-Borges, Meghan A Wallace, Thomas J Hannan, Carey-Ann D Burnham, Scott J Hultgren and 1 more

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Anne L RosenDivision of Allergy and Immunology, Department of Medicine, Washington University School of Medicine, St. Louis, MO.
Michael A LintDivision of Allergy and Immunology, Department of Medicine, Washington University School of Medicine, St. Louis, MO.
Dayne H VoelkerDivision of Allergy and Immunology, Department of Medicine, Washington University School of Medicine, St. Louis, MO.
Nicole M GilbertDivision of Infectious Diseases, Department of Pediatrics, Washington University School of Medicine, St. Louis, MO.
Christopher P TomeraDivision of Allergy and Immunology, Department of Medicine, Washington University School of Medicine, St. Louis, MO.
Jesús Santiago-BorgesDivision of Allergy and Immunology, Department of Medicine, Washington University School of Medicine, St. Louis, MO.
Meghan A WallaceDepartment of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO.
Thomas J HannanDepartment of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO.
Carey-Ann D BurnhamDivision of Infectious Diseases, Department of Pediatrics, Washington University School of Medicine, St. Louis, MO.
Scott J HultgrenCenter for Women's Infectious Disease Research, Washington University School of Medicine, St. Louis, MO.
Andrew L KauDivision of Allergy and Immunology, Department of Medicine, Washington University School of Medicine, St. Louis, MO.
Washington University in St. Louis · US

Funding

TRAINING PROGRAM IN CELLULAR AND MOLECULAR BIOLOGYT32GM007067 · NIGMS · WASHINGTON UNIVERSITY · PI TRUE-KROB, HEATHER L · 1985 to 2020
$20.4M
Mucosal Immune Defense Mechanisms of the Urinary BladderU01AI095542 · NIAID · WASHINGTON UNIVERSITY · PI COLONNA, MARCO, HULTGREN, SCOTT J. · 2011 to 2020
$9.8M
Harnessing Antibody Responses to Prevent and Treat Urinary Tract InfectionsR01AI165915 · NIAID · WASHINGTON UNIVERSITY · PI Andrew Leon Kau · 2022 to 2026
$3.1M
Mucosal Immune Defense Mechanisms of the Urinary BladderR01DK132327 · NIDDK · WASHINGTON UNIVERSITY · PI MARCO COLONNA, SCOTT J. HULTGREN · 2023 to 2026
$2.5M
Role of Gardnerella vaginalis in the Urinary TractK01DK110225 · NIDDK · WASHINGTON UNIVERSITY · PI GILBERT, NICOLE MARIE · 2017 to 2021
$560k
NIAID NIH HHS R01 AI165915NIAID NIH HHS U01 AI095542NIDDK NIH HHS K01 DK110225NIDDK NIH HHS R01 DK132327NIGMS NIH HHS T32 GM007067
6 · The paper itself

Abstract

Millions suffer from urinary tract infections (UTIs) worldwide every year with women accounting for the majority of cases. Uropathogenic

Identifiers

PMID37873489
PMCPMC10592744
OpenAlexW4387653805

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.