Evidence map›Paper›PMID 37873467›Full record

ArticlebioRxiv : the preprint server for biology2023

Cytochrome P450 and Epoxide Hydrolase Metabolites in Aβ and tau-induced Neurodegeneration: Insights from

Morteza Sarparast, Jennifer Hinman, Elham Pourmand, Derek Vonarx, Leslie Ramirez, Wenjuan Ma, Nicole F Liachko, Jamie K Alan, Kin Sing Stephen Lee

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Morteza SarparastDepartment of Pharmacology and Toxicology, Michigan State University, East Lansing, MI, USA.
Jennifer HinmanDepartment of Chemistry, Michigan State University, East Lansing, MI, USA.
Elham PourmandDepartment of Chemistry, Michigan State University, East Lansing, MI, USA.
Derek VonarxDepartment of Chemistry, Michigan State University, East Lansing, MI, USA.
Leslie RamirezDepartment of Pharmacology and Toxicology, Michigan State University, East Lansing, MI, USA.
Wenjuan MaCenter for Statistical Training and Consulting (CSTAT), Michigan State University, East Lansing, MI, USA.
Nicole F LiachkoGeriatrics Research Education and Clinical Center, Veterrans Affairs Puget Sound Health Care System, Seattle, WA, USA.
Jamie K AlanDepartment of Pharmacology and Toxicology, Michigan State University, East Lansing, MI, USA.
Kin Sing Stephen LeeDepartment of Pharmacology and Toxicology, Michigan State University, East Lansing, MI, USA.
Michigan State University · USUniversity of Washington · US

Funding

Enhancing and expanding the CGC Strain CollectionP40OD010440 · OD · UNIVERSITY OF MINNESOTA · PI Aric L Daul, Ann E. Rougvie · 2012 to 2026
$7.5M
Oxylipins, aging and Alzheimer’s diseaseR03AG075465 · NIA · MICHIGAN STATE UNIVERSITY · PI LEE, KIN SING STEPHEN · 2022 to 2023
$305k
NIA NIH HHS R03 AG075465NIH HHS P40 OD010440
6 · The paper itself

Abstract

This study aims to uncover potent cytochrome P450 (CYP) and epoxide hydrolase (EH) metabolites implicated in Aβ and/or tau-induced neurodegeneration, independent of neuroinflammation, by utilizing

Identifiers

PMID37873467
PMCPMC10592936
OpenAlexW4387242924

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.