Evidence map›Paper›PMID 37873460›Full record

ArticlebioRxiv : the preprint server for biology2023

Decoding transcriptomic signatures of Cysteine String Protein alpha-mediated synapse maintenance.

Na Wang, Biqing Zhu, Mary Alice Allnutt, Rosalie M Grijalva, Hongyu Zhao, Sreeganga S Chandra

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Na WangDepartments of Neurology and Neuroscience, Yale University, New Haven, CT, USA.
Biqing ZhuProgram of Computational Biology and Bioinformatics, Yale University, New Haven, CT, USA.
Mary Alice AllnuttDepartments of Neurology and Neuroscience, Yale University, New Haven, CT, USA.
Rosalie M GrijalvaInterdepartmental Neuroscience Program, Yale University, New Haven, CT, USA.
Hongyu ZhaoProgram of Computational Biology and Bioinformatics, Yale University, New Haven, CT, USA.
Sreeganga S ChandraDepartments of Neurology and Neuroscience, Yale University, New Haven, CT, USA.
Yale University · US

Funding

NEUROBIOLOGY OF CORTICAL SYSTEMST32NS007224 · NINDS · YALE UNIVERSITY · PI CARDIN, JESSICA A · 1985 to 2025
$4.6M
Roles of the CSPalpha Chaperone Complex in Presynaptic Maintenance and ANCLR01NS083846 · NINDS · YALE UNIVERSITY · PI CHANDRA, SREEGANGA S · 2014 to 2018
$2.2M
Investigating the Functions of RME8 in Parkinson's DiseaseR21NS132546 · NINDS · YALE UNIVERSITY · PI CHANDRA, SREEGANGA S · 2023 to 2024
$461k
NINDS NIH HHS R01 NS083846NINDS NIH HHS R21 NS132546NINDS NIH HHS T32 NS007224
6 · The paper itself

Abstract

Synapse maintenance is essential for generating functional circuitry and decrement in this process is a hallmark of neurodegenerative disease. While we are beginning to understand the basis of synapse formation, much less is known about synapse maintenance

Indexed as

autophagosomechaperoneCSPαNeurexin1-Neuroligin 1synapse loss

Identifiers

PMID37873460
PMCPMC10592922
OpenAlexW4387309720

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.