Evidence map›Paper›PMID 37873359›Full record

ArticlebioRxiv : the preprint server for biology2023

Multidimensional Analysis of the Adult Human Heart in Health and Disease using Hierarchical Phase-Contrast Tomography (HiP-CT).

J Brunet, A C Cook, C L Walsh, J Cranley, P Tafforeau, K Engel, C Berruyer, E Burke O'Leary, A Bellier, R Torii and 5 more

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

15 authors.

J BrunetDepartment of Mechanical Engineering, University College London, London, UK.
A C CookUCL Institute of Cardiovascular Science, London, UK.
C L WalshDepartment of Mechanical Engineering, University College London, London, UK.
J CranleyWellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, UK.
P TafforeauEuropean Synchrotron Radiation Facility, Grenoble, France.
K EngelSiemens Healthineers, Erlangen, Germany.
C BerruyerDepartment of Mechanical Engineering, University College London, London, UK.
E Burke O'LearyDepartment of Mechanical Engineering, University College London, London, UK.
A BellierLaboratoire d'Anatomie des Alpes Françaises (LADAF), Université Grenoble Alpes, Grenoble, F.
R ToriiDepartment of Mechanical Engineering, University College London, London, UK.
C WerleinInstitute of Pathology, Hannover Medical School, Hannover, Germany.
D D JonigkBiomedical Research in End-stage and Obstructive Lung Disease Hannover (BREATH), German Lung Research Centre (DZL), Hannover, Germany.
M AckermannInstitute of Pathology and Molecular Pathology, Helios University Clinic Wuppertal, University of Witten/Herdecke, Wuppertal, Germany.
K DollmanEuropean Synchrotron Radiation Facility, Grenoble, France.
P D LeeDepartment of Mechanical Engineering, University College London, London, UK.

Funding

Adult Tissue Morphogenesis: Functional Regulation of Intussusceptive AngiogenesisR01HL094567 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI MENTZER, STEVEN · 2009 to 2016
$3.2M
Formation of the Elastin Line Element in the Developing LungF32HL134229 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI VALENZUELA, CRISTIAN DAVID · 2016 to 2016
$57k
NHLBI NIH HHS F32 HL134229NHLBI NIH HHS R01 HL094567
6 · The paper itself

Abstract

Cardiovascular diseases (CVDs) are a leading cause of death worldwide. Current clinical imaging modalities provide resolution adequate for diagnosis but are unable to provide detail of structural changes in the heart, across length-scales, necessary for understanding underlying pathophysiology of disease. Hierarchical Phase-Contrast Tomography (HiP-CT), using new (4

Identifiers

PMID37873359
PMCPMC10592740

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.