Evidence map›Paper›PMID 37873278›Full record

ArticlebioRxiv : the preprint server for biology2023

Identification of a convergent spinal neuron population that encodes itch.

Tayler D Sheahan, Charles A Warwick, Abby Y Cui, David A A Baranger, Vijay J Perry, Kelly M Smith, Allison P Manalo, Eileen K Nguyen, H Richard Koerber, Sarah E Ross

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 3 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Tayler D SheahanPittsburgh Center for Pain Research and Department of Neurobiology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.ORCID 0000-0002-5015-0600
Charles A WarwickPittsburgh Center for Pain Research and Department of Neurobiology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.ORCID 000-0001-6244-9821
Abby Y CuiPittsburgh Center for Pain Research and Department of Neurobiology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
David A A BarangerDepartment of Psychological and Brain Sciences, Washington University in St. Louis, St. Louis Missouri, USA.ORCID 0000-0002-6659-357X
Vijay J PerryPittsburgh Center for Pain Research and Department of Neurobiology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Kelly M SmithPittsburgh Center for Pain Research and Department of Neurobiology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Allison P ManaloPittsburgh Center for Pain Research and Department of Neurobiology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Eileen K NguyenPittsburgh Center for Pain Research and Department of Neurobiology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
H Richard KoerberPittsburgh Center for Pain Research and Department of Neurobiology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.ORCID 0000-0002-8729-5379
Sarah E RossPittsburgh Center for Pain Research and Department of Neurobiology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
University of Pittsburgh · USUniversity of California, Los Angeles · USWashington University in St. Louis · US

Funding

Defining Mechanisms of Pain Relief Associated with Dorsal Root Ganglion and Spinal Cord StimulationRM1NS128775 · NINDS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI KOERBER, H RICHARD, LEMPKA, SCOTT F · 2022 to 2025
$9.6M
Investigating the Neural Circuits of ItchR01AR063772 · NIAMS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI H Richard Koerber, Sarah Elizabeth Ross · 2013 to 2026
$6.9M
Molecular genetic dissection of the spinal microcircuits of wind-upR01NS096705 · NINDS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI KOERBER, H RICHARD, ROSS, SARAH ELIZABETH · 2016 to 2025
$5.1M
Understanding spinal neuropeptide signaling in itchK99NS126569 · NINDS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI SHEAHAN, TAYLER · 2022 to 2023
$244k
Understanding the spinal circuitry of coldF32NS110155 · NINDS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI SHEAHAN, TAYLER · 2018 to 2021
$225k
NIAMS NIH HHS R01 AR063772NINDS NIH HHS F32 NS110155NINDS NIH HHS K99 NS126569NINDS NIH HHS R01 NS096705NINDS NIH HHS RM1 NS128775
6 · The paper itself

Abstract

Itch is a protective sensation that drives scratching. Although specific cell types have been proposed to underlie itch, the neural circuit basis for itch remains unclear. Here, we used two-photon Ca

Identifiers

PMID37873278
PMCPMC10592866
OpenAlexW4387244708

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.