ArticlebioRxiv : the preprint server for biology2023
A DRP-like pseudoenzyme coordinates with MICOS to promote cristae architecture.
Abhishek Kumar, Mehmet Oguz Gok, Kailey N Nguyen, Michael L Reese, Jeremy G Wideman, Sergio A Muñoz-Gómez, Jonathan R Friedman
Open access · greenAbstract readPreprint
In one paragraphArticle in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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0citing papers in PubMed
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What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
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3 · Its place in the literatureWho cites it
0 citing papers in PubMed, 2 citations in OpenAlex.
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4 · The recordCorrections and comments
5 · Who and what moneyAuthors and funding
7 authors at 3 institutions in 1 country.
Abhishek KumarDepartment of Cell Biology, University of Texas Southwestern Medical Center, Dallas, TX.
Mehmet Oguz GokDepartment of Cell Biology, University of Texas Southwestern Medical Center, Dallas, TX.
Kailey N NguyenDepartment of Cell Biology, University of Texas Southwestern Medical Center, Dallas, TX.
Michael L ReeseDepartment of Pharmacology, University of Texas Southwestern Medical Center, Dallas, TX.
Jeremy G WidemanCenter for Mechanisms of Evolution, Biodesign Institute, School of Life Sciences, Arizona State University, Tempe, AZ.
Sergio A Muñoz-GómezDepartment of Biological Sciences, Purdue University, West Lafayette, IN.
Jonathan R FriedmanDepartment of Cell Biology, University of Texas Southwestern Medical Center, Dallas, TX.
The University of Texas Southwestern Medical Center · USArizona State University · USPurdue University West Lafayette · US
Funding
UT Southwestern Medical Center Simmons Comprehensive Cancer CenterP30CA142543 · NCI · UT SOUTHWESTERN MEDICAL CENTER · PI MELANIE H. COBB · 2010 to 2026
$53.7MSpatial Organization of the Mitochondrial Inner MembraneR35GM137894 · NIGMS · UT SOUTHWESTERN MEDICAL CENTER · PI Jonathan R. Friedman · 2020 to 2026
$3.1MKinase regulation of trafficking at the Toxoplasma intravacuolar networkR01AI150715 · NIAID · UT SOUTHWESTERN MEDICAL CENTER · PI REESE, MICHAEL LLOYD · 2020 to 2024
$2.0MSpinning Disk Confocal for UT SouthwesternS10OD028630 · OD · UT SOUTHWESTERN MEDICAL CENTER · PI LUBY-PHELPS, KATHERINE J · 2020 to 2020
$600kElucidating the role of the Toxoplasma residual body in cytoskeleton turnoverR21AI171227 · NIAID · UT SOUTHWESTERN MEDICAL CENTER · PI REESE, MICHAEL LLOYD · 2023 to 2024
$451kTEM for UT Southwestern Electron Microscopy Core FacilityS10OD021685 · OD · UT SOUTHWESTERN MEDICAL CENTER · PI LUBY-PHELPS, KATHERINE J · 2017 to 2017
$398kNCI NIH HHS P30 CA142543NIAID NIH HHS R01 AI150715NIAID NIH HHS R21 AI171227NIGMS NIH HHS R35 GM137894NIH HHS S10 OD021685NIH HHS S10 OD028630
6 · The paper itselfAbstract
Mitochondrial cristae architecture is crucial for optimal respiratory function of the organelle. Cristae shape is maintained in part by the mitochondrial inner membrane-localized MICOS complex. While MICOS is required for normal cristae morphology, the precise mechanistic role of each of the seven human MICOS subunits, and how the complex coordinates with other cristae shaping factors, has not been fully determined. Here, we examine the MICOS complex in
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PMID37873150
PMCPMC10592917
OpenAlexW4387332638
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