Evidence map›Paper›PMID 37873098›Full record

ArticlebioRxiv : the preprint server for biology2023

Modular multiwell viscoelastic hydrogel platform for two- and three-dimensional cell culture applications.

Mackenzie L Skelton, James L Gentry, Leilani R Astrab, Joshua A Goedert, E Brynn Earl, Emily L Pham, Tanvi Bhat, Steven R Caliari

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Mackenzie L SkeltonDepartment of Biomedical Engineering, University of Virginia, Charlottesville, Virginia 22903.
James L GentryDepartment of Biomedical Engineering, University of Virginia, Charlottesville, Virginia 22903.
Leilani R AstrabDepartment of Biomedical Engineering, University of Virginia, Charlottesville, Virginia 22903.
Joshua A GoedertDepartment of Biomedical Engineering, University of Virginia, Charlottesville, Virginia 22903.
E Brynn EarlDepartment of Biomedical Engineering, University of Virginia, Charlottesville, Virginia 22903.
Emily L PhamDepartment of Biomedical Engineering, University of Virginia, Charlottesville, Virginia 22903.
Tanvi BhatDepartment of Psychology, University of Virginia, Charlottesville, Virginia 22903.
Steven R CaliariDepartment of Biomedical Engineering, University of Virginia, Charlottesville, Virginia 22903.

Funding

Designing cell-instructive hydrogels to understand and exploit mechanobiologyR35GM138187 · NIGMS · UNIVERSITY OF VIRGINIA · PI CALIARI, STEVEN · 2020 to 2024
$1.8M
NIGMS NIH HHS R35 GM138187
6 · The paper itself

Abstract

Hydrogels have gained significant popularity as model platforms to study the reciprocal interactions between cells and their microenvironment. While hydrogel tools to probe many characteristics of the extracellular space have been developed, fabrication approaches remain challenging and time-consuming, limiting multiplexing or widespread adoption. Thus, we have developed a modular fabrication approach to generate distinct hydrogel microenvironments within 96-well plates for increased throughput of fabrication as well as integration with existing high-throughput assay technologies. This approach enables

Indexed as

disease modelinghigh-throughputhydrogelsmultiwell plate

Identifiers

PMID37873098
PMCPMC10592709

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.