Evidence map›Paper›PMID 37873059›Full record

ArticleTranslational neuroscience2023

7-Day National Institutes of Health Stroke Scale as a surrogate marker predicting ischemic stroke patients' outcome following endovascular therapy.

Yuzheng Lai, Eric Jou, Mohammad Mofatteh, Thanh N Nguyen, Jamie Sin Ying Ho, Francesco Diana, Adam A Dmytriw, Jianfeng He, Wenshan Yan, Yiying Chen and 5 more

Open access · goldAbstract read
In one paragraph

Article in Translational neuroscience, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 2 pooled it
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 2 syntheses or guidelines pooled it, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 9 institutions in 5 countries.

Yuzheng LaiDepartment of Neurology, Guangdong Provincial Hospital of Integrated Traditional Chinese and Western Medicine, Foshan, Guangdong, China.
Eric JouSchool of Clinical Medicine, University of Cambridge, Cambridge, United Kingdom.
Mohammad MofattehSchool of Medicine, Dentistry and Biomedical Sciences, Queen's University Belfast, Belfast, United Kingdom.
Thanh N NguyenDepartment of Neurology, Radiology, Boston University Chobanian & Avedisian School of Medicine, Boston, MA, United States.
Jamie Sin Ying HoDepartment of Medicine, Royal Free London NHS Foundation Trust, London, United Kingdom.
Francesco DianaDepartment of Neuroradiology, A.O.U. San Giovanni di Dio e Ruggi d'Aragona, University of Salerno, Salerno, Italy.
Adam A DmytriwNeuroendovascular Program, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
Jianfeng HeDepartment of Neurology, Guangdong Provincial Hospital of Integrated Traditional Chinese and Western Medicine, Foshan, Guangdong, China.
Wenshan YanDepartment of Neurology, Guangdong Provincial Hospital of Integrated Traditional Chinese and Western Medicine, Foshan, Guangdong, China.
Yiying ChenDepartment of Neurology, Guangdong Provincial Hospital of Integrated Traditional Chinese and Western Medicine, Foshan, Guangdong, China.
Zile YanDepartment of Neurology and Advanced National Stroke Center, Foshan Sanshui District People's Hospital, Foshan, 528100, Guangdong, China.
Hao SunDepartment of Neurology, Guangdong Provincial Hospital of Integrated Traditional Chinese and Western Medicine, Foshan, Guangdong, China.
Leonard L YeoDivision of Neurology, Department of Medicine, National University Health System, Singapore, Singapore.
Yimin ChenDepartment of Neurology and Advanced National Stroke Center, Foshan Sanshui District People's Hospital, Foshan, 528100, Guangdong, China.
Sijie ZhouDepartment of Surgery of Cerebrovascular Diseases, First People's Hospital of Foshan, Foshan, 528000, Guangdong, China.
Foshan Hospital of TCM · CNNational University of Singapore · SGBoston University · USFirst People's Hospital of Foshan · CNHarvard University · USQueen's University Belfast · GBRoyal Free London NHS Foundation Trust · GBUniversity of Cambridge · GBUniversity of Salerno · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Early neurological deterioration after endovascular thrombectomy (EVT) is associated with poor prognosis. National Institutes of Health Stroke Scale (NIHSS) score measured at 24 h after EVT may be a better outcome predictor than other methods that focus on changes in NIHSS. Nevertheless, clinical fluctuations in ischemic stroke patients during the immediate phase after symptoms onset are well recognized. Therefore, a delayed NIHSS evaluation may improve prognostic accuracy. We evaluate the 7-day NIHSS in predicting long-term patient outcomes after EVT. Methods: This was a multi-center retrospective cohort study of 300 consecutive ischemic stroke patients with large vessel occlusion who underwent EVT at three-stroke centers in China from August 2018 to March 2022. NIHSS was recorded on admission, pre-EVT, 24 h, and 7 days after EVT. Results: A total of 236 eligible patients were subdivided into two groups: 7-day NIHSS ≤6 and NIHSS >6 post-EVT. 88.29% achieved a favorable outcome (modified Rankin Scale 0-2) in the NIHSS ≤6 group compared to 15.20% in the NIHSS >6 group at 90 days, and an improved favorable outcome in the former group was observed after adjusting for potential confounding factors (adjusted odds ratio 39.7, 95% confidence interval, 17.5-89.7, Conclusion: The 7-day NIHSS score may be a reliable predictor of 90-day stroke patient outcome after EVT.

Indexed as

endovascular thrombectomymechanical thrombectomyNIHSSprognosisstroke

Identifiers

PMID37873059
PMCPMC10590605
OpenAlexW4387788310

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.