Evidence map›Paper›PMID 37873033›Full record

ArticleChem2023

EDA Photochemistry: Mechanistic Investigations and Future Opportunities.

Alan K Wortman, Corey R J Stephenson

Open access · greenAbstract read
In one paragraph

Article in Chem, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed
72.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 183 citations in OpenAlex.

  1. Visible light promoted chalcone transformations and their prominence for the synthesis of functionalized molecules: a review.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2026
    Review
  2. Article
  3. Article
  4. Article
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  6. Article
  7. Article
  8. Deprotection of benzyl ethersGreen chemistry : an international journal and green chemistry resource : GC · 2026
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Multicomponent Photochemical Assembly of C(spACS organic & inorganic Au · 2026
    Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. EDA Complex-Mediated C(spEuropean journal of organic chemistry · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Alan K WortmanWillard Henry Dow Laboratory, Department of Chemistry, University of Michigan, 930 North University Avenue, Ann Arbor, Michigan 48109, United States.
Corey R J StephensonWillard Henry Dow Laboratory, Department of Chemistry, University of Michigan, 930 North University Avenue, Ann Arbor, Michigan 48109, United States.
University of Michigan · US

Funding

Photochemical synthesis of bioactive moleculesR01GM127774 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI STEPHENSON, COREY · 2018 to 2021
$1.9M
Free radical strategies for bioactive molecule synthesis - Undergraduate SupplementR35GM144286 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI STEPHENSON, COREY · 2022 to 2024
$1.8M
NIGMS NIH HHS R01 GM127774NIGMS NIH HHS R35 GM144286
6 · The paper itself

Abstract

Recently, organic synthesis has seen a renaissance in radical chemistry due to the accessibility of mild methods for radical generation using visible light. While renewed interest in synthetic radical chemistry has been driven by the advent of photoredox catalysis, a resurgence of electron donor-acceptor (EDA) photochemistry has also led to many new radical transformations. Similar to photoredox catalysis, EDA photochemistry involves light-promoted single-electron transfer pathways. However, the mechanism of electron transfer in EDA systems is unique wherein the lifetimes of radical intermediates are often shorter due to competitive back-electron transfer. Distinguishing between EDA and photoredox mechanisms can be challenging since they can form identical products. In this perspective, we seek to provide insight on the mechanistic studies which can distinguish between EDA and photoredox manifolds. Additionally, we highlight some key challenges in EDA photochemistry and suggest future goals which could advance the synthetic potential of this field of research.

Indexed as

EDA complexMechanismPhotocatalysisPhotochemistryPhotoredox

Identifiers

PMID37873033
PMCPMC10588808
OpenAlexW4384701179

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.