ArticleMicrobiome2023
Pet cats may shape the antibiotic resistome of their owner's gut and living environment.
Article in Microbiome, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed, 40 citations in OpenAlex.
- Animal gut microbes and microbiomes in the 21st century and beyond.Science China. Life sciences · 2026Review
- Genome-resolved and culture-based atlas of the feline gut microbiome enables host-adapted probiotic development.NPJ biofilms and microbiomes · 2026Article
- Society and the Microbiome: A Biopsychosocial Window Into Comprehensive Well-Being: A Review.Health science reports · 2026Article
- Antibiotic resistance genes in companion animals and humans driven by the gut microbial communities: composition, distribution, and implications.BMC veterinary research · 2026Article
- Tick-vectored mobilization of antibiotic resistance genes: transboundary dissemination across wildlife-livestock-vector-environment interfaces.NPJ biofilms and microbiomes · 2026Article
- [Detection and Distribution Characteristics of Antibiotic Resistance Genes in Companion Animals].Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2026Article
- Benchmarking: A Tool for Veterinary Practices to Improve Prudent Use of Antibiotics in Cats and Dogs in Switzerland.Antibiotics (Basel, Switzerland) · 2026Article
- The domestic cat microbiome: mapping knowledge gaps through scientometric analysis in feline microbial research.Veterinary research communications · 2025Review
- Mobilome-mediated transcriptional activation of biosynthetic gene clusters and its impact on strain competitiveness in food fermentation microbiomes.Microbiome · 2025Article
- Early Life Exposure to Manure-Fertilized Soil Shapes the Gut Antibiotic Resistome.Environment & health (Washington, D.C.) · 2025Article
- Natural Microbiota of Dogs and Cats as a Source and Vector of Resistance Genes-Clinical Significance.International journal of molecular sciences · 2025Review
- Article
- Characteristics ofInternational journal of molecular sciences · 2025Article
- Microbial Interconnections in One Health: A Critical Nexus Between Companion Animals and Human Microbiomes.Microorganisms · 2025Review
- What Are the Drivers Triggering Antimicrobial Resistance Emergence and Spread? Outlook from a One Health Perspective.Antibiotics (Basel, Switzerland) · 2025Review
- The pet café is a neglected site for transmission of antimicrobial-resistantMicrobial genomics · 2025Article
- Article
- Profiling the composition of resistome and bacteriome in the upper respiratory tract of domestic cats with respiratory signs in China.Microbiome research reports · 2025Article
- Metagenomic insights into the resistome, mobilome, and virulome of dogs with diverse lifestyles.Animal microbiome · 2024Article
- Antimicrobial Use in Cats in a University Veterinary Hospital in Central Italy: A Retrospective Study.Antibiotics (Basel, Switzerland) · 2024Article
Corrections and comments
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Authors and funding
9 authors at 5 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCompanion animals can contribute to the physical and mental health of people and often live in very close association with their owners. However, the antibiotic resistome carried by companion animals and the impact they have on their owners and living environment remain unclear. In this study, we compared the ARG profiles of cats, humans, and their living environments using metagenomic analysis to identify the core ARGs in the cat and human gut and explore the potential impact of cats on ARGs in the human gut through the environment.
resultsResults showed that the abundance of ARGs in the cat gut was significantly higher than that in the human gut (P < 0.0001), with aminoglycoside and tetracycline resistance genes being the dominant ARGs in the cat gut. There was no significant difference in the abundance of total ARGs in the guts of cat owners and non-owners (P > 0.05). However, the abundance of aminoglycoside resistance genes including APH(2'')-IIa and AAC(6')-Im was significantly higher in cat owners than that in non-cat owners (P < 0.001). Also, ARG abundance was positively correlated with the frequency of cat activity in the living environment. Enterobacteriaceae was the dominant ARG host co-occurring in the cat gut, human gut, and living environment.
conclusionsOur results show that cats may shape the living environment resistome and thus the composition of some ARGs in the human gut, highlighting the importance of companion animal environment health. Video Abstract.
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