Evidence map›Paper›PMID 37872518›Full record

ArticleBMC ophthalmology2023

Prevalence and associated factors of diabetic retinopathy among people with diabetes screened using fundus photography at a community diabetic retinopathy screening program in Nepal.

Raba Thapa, Sanjita Sharma, Eli Pradhan, Sushma Duwal, Manish Poudel, Krishna Gopal Shrestha, Govinda Prasad Paudyal

Open access · goldAbstract read
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Article in BMC ophthalmology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

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0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Raba ThapaTilganga Institute of Ophthalmology, Kathmandu, PO Box: 561, Nepal. rabathapa@live.com.
Sanjita SharmaTilganga Institute of Ophthalmology, Kathmandu, PO Box: 561, Nepal.
Eli PradhanTilganga Institute of Ophthalmology, Kathmandu, PO Box: 561, Nepal.
Sushma DuwalTilganga Institute of Ophthalmology, Kathmandu, PO Box: 561, Nepal.
Manish PoudelTilganga Institute of Ophthalmology, Kathmandu, PO Box: 561, Nepal.
Krishna Gopal ShresthaTilganga Institute of Ophthalmology, Kathmandu, PO Box: 561, Nepal.
Govinda Prasad PaudyalTilganga Institute of Ophthalmology, Kathmandu, PO Box: 561, Nepal.
Tilganga Institute of Ophthalmology · NP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThis study aimed to assess the prevalence and associated factors of diabetic retinopathy (DR) and vision threatening DR (VTDR) among people with diabetes screened using fundus photography in Nepal.

methodsThis is a retrospective study among people with diabetes presented for DR screening using fundus photography from 2013 to 2019. Detailed demographics, duration of diabetes, medical history, visual acuity, and grading of DR on fundus photography were analyzed. Fundus camera used in the study were;Topcon digital fundus camera 900 CXR and digital portable fundus cameras (Nidek-10 portable non-mydriatric fundus camera; Versacam & Trade & Alpha, France), and a Zeiss portable fundus camera (Zeiss Visucout 100). Macula centred and disc centred 45 degree two images were taken from each eye. Pupil were dilated in cases where there was media haze in un-dilated cases. DR was graded using early treatment diabetic retinopathy study criteria. The images were graded by fellowship trained retina specialist. DR prevalence included any DR changes in one or both eyes.

resultsTotal of 25,196 patients with diabetes were enrolled. Mean age was 54.2 years with Standard Deviation (S.D):12.9 years, ranging from 6 years to 97 years. Type 1 and type 2 diabetes comprised of 451 people (1.79%) and 24,747 (98.21%) respectively. Overall, 1.8% of the images were un-gradable. DR prevalence was 19.3% (95% Confidence Interval (CI): 18.8 - 19.7%). DR prevalence in type 1 and type 2 diabetes was 15.5% (95% CI: 12.5 - 18.6%) and 19.3% (CI: 18.8 - 19.8%) respectively. Clinically significant macular edema (CSME) was found in 5.9% (95% CI: 5.6-6.2%) and VTDR in 7.9% (95% CI: 7.7-8.3%). In multivariate analysis, our study revealed strong evidence to suggest that there is meaningful association between DR and VTDR with duration of diabetes, diabetic foot, diabetic neuropathy, agriculture occupation, those under oral hypoglycaemic agents or insulin or both as compared to those under diet only, and presenting visual acuity > 0.3LogMAR.

conclusionPrevalence and associated factors for DR and VTDR were similar to other DR screening programs in the region. Emphasis on wider coverage of DR screening could help for timely detection and treatment of STDR to avoid irreversible blindness.

Indexed as

Diabetes Mellitus, Type 2Diabetic RetinopathyHumansMass ScreeningMiddle AgedNepalPhotographyPrevalenceRetrospective StudiesAssociated factorsDiabetic retinopathyNepalScreeningSight threatening diabetic retinopathy

Identifiers

PMID37872518
PMCPMC10594880
OpenAlexW4387880003

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.