Evidence map›Paper›PMID 37872451›Full record

ArticleNature genetics2023

Post-zygotic brain mosaicism as a result of partial reversion of pre-zygotic aneuploidy.

Changuk Chung, Xiaoxu Yang, Joseph G Gleeson

Abstract read
In one paragraph

Article in Nature genetics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Disease insights from brain somatic mosaicism.Experimental & molecular medicine · 2026
    Review
  2. [Sperm Mosaic Variants and Their Influence on the Offspring].Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2024
    Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Changuk ChungRady Children's Institute of Genomic Medicine, Department of Neurosciences, University of California, San Diego, La Jolla, CA, USA.
Xiaoxu YangRady Children's Institute of Genomic Medicine, Department of Neurosciences, University of California, San Diego, La Jolla, CA, USA.ORCID 0000-0003-0219-0023
Joseph G GleesonRady Children's Institute of Genomic Medicine, Department of Neurosciences, University of California, San Diego, La Jolla, CA, USA. jogleeson@health.ucsd.edu.ORCID 0000-0002-6713-8018

Funding

Mosaicism in focal cortical dysplasias spectrum seen in neuropsychiatric diseaseU01MH108898 · NIMH · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI GLEESON, JOSEPH G · 2015 to 2019
$5.1M
Molecular characterization of HemimegalencephalyR01NS083823 · NINDS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI GLEESON, JOSEPH G, MATHERN, GARY W. · 2013 to 2017
$3.1M
Origins of Brain Somatic Mosaicism in Developmental Brain DiseaseR01MH124890 · NIMH · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI GLEESON, JOSEPH G · 2021 to 2025
$1.5M
Understanding genomic stability between generations by assessing mutational burdens in single spermsR00HD111686 · NICHD · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH · PI Xiaoxu Yang · 2025 to 2026
$498k
Mechanisms controlling HIV latency and pathogenesis in microgliaR21MH134401 · NIMH · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI SCHLACHETZKI, JOHANNES CAROLUS MAGNUS, YANG, XIAOXU · 2023 to 2023
$435k
Understanding genomic stability betweengenerations by assessing mutational burdens in single spermsK99HD111686 · NICHD · UNIVERSITY OF UTAH · PI YANG, XIAOXU · 2023 to 2024
$232k
NICHD NIH HHS K99 HD111686NICHD NIH HHS R00 HD111686NIMH NIH HHS R01 MH124890NIMH NIH HHS R21 MH134401NIMH NIH HHS U01 MH108898NINDS NIH HHS R01 NS083823
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID37872451
PMCPMC10842191

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.