Evidence map›Paper›PMID 37872406›Full record

ArticleEuropean radiology experimental2023

Diagnostic performance of short noncontrast biparametric 3-T MRI for tonsillar infections: comparison with a full protocol including contrast-enhanced sequences.

Jari-Pekka Vierula, Janne Nurminen, Ville Jussila, Mikko Nyman, Jaakko Heikkinen, Bernd Pape, Kaarlo Sorvettula, Kimmo Mattila, Jussi Hirvonen

Open access · goldAbstract read
In one paragraph

Article in European radiology experimental, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Jari-Pekka VierulaDepartment of Radiology, Turku University Hospital, Turku, Finland. jptvie@gmail.com.ORCID http://orcid.org/0009-0006-5933-5421
Janne NurminenDepartment of Radiology, Turku University Hospital, Turku, Finland.
Ville JussilaDepartment of Radiology, Turku University Hospital, Turku, Finland.
Mikko NymanDepartment of Radiology, Turku University Hospital, Turku, Finland.
Jaakko HeikkinenDepartment of Radiology, Turku University Hospital, Turku, Finland.
Bernd PapeDepartment of Biostatistics, Turku University Hospital, Turku, Finland.
Kaarlo SorvettulaMedical Imaging Center, Department of Radiology, Tampere University and Tampere University Hospital, Tampere, Finland.
Kimmo MattilaDepartment of Radiology, Turku University Hospital, Turku, Finland.
Jussi HirvonenDepartment of Radiology, Turku University Hospital, Turku, Finland.
Turku University Hospital · FITampere University Hospital · FI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWe investigated whether a short, 5-min magnetic resonance imaging (MRI) protocol consisting of only axial T2-weighted and diffusion-weighted imaging (DWI) sequences can discriminate between tonsillar infections, peritonsillar abscesses and deeply extending abscesses in a retrospective, blinded, multireader setting.

methodsWe included patients sent by emergency physicians with suspected pharyngotonsillar infections who underwent emergency neck 3-T MRI from April 1 2013 to December 31 2018. Three radiologists (with 10-16 years of experience) reviewed the images for abscesses and their extension into deep neck spaces. Data were reviewed first using only axial T2-weighted Dixon images and DWI (short protocol) and second including other sequences and contrast-enhanced T1-weighted Dixon images (full protocol). Diagnostic accuracy, interobserver agreement, and reader confidence were measured. Surgical findings and clinical course served as standard of reference.

resultsThe final sample consisted of 52 patients: 13 acute tonsillitis with no abscesses, 19 peritonsillar abscesses, and 20 deeply extending abscesses. Using the short protocol, diagnostic accuracy for abscesses across all readers was good-to-excellent: sensitivity 0.93 (95% confidence interval 0.87-0.97), specificity 0.85 (0.70-0.93), accuracy 0.91 (0.85-0.95). Using the full protocol, respective values were 0.98 (0.93-1.00), 0.85 (0.70-0.93), and 0.95 (0.90-0.97), not significantly different compared with the short protocol. Similar trends were seen with detecting deep extension. Interobserver agreement was similar between protocols. However, readers had higher confidence in diagnosing abscesses using the full protocol.

conclusionsShort MRI protocol showed good-to-excellent accuracy for tonsillar abscesses. Contrast-enhanced images improved reader confidence but did not affect diagnostic accuracy or interobserver agreement. RELEVANCE STATEMENT: Short protocol consisting only of T2-weighted Dixon and DWI sequences can accurately image tonsillar abscesses, which may improve feasibility of emergency neck MRI. KEY POINTS: • The short 3-T MRI protocol (T2-weighted images and DWI) was faster (5 min) than the full protocol including T1-weighted contrast-enhanced images (24 min). • The short 3-T MRI protocol showed good diagnostic accuracy for pharyngotonsillar abscesses. • Contrast-enhanced sequences improved reader confidence but did not impact diagnostic accuracy or interobserver agreement.

Indexed as

Peritonsillar AbscessContrast MediaDiffusion Magnetic Resonance ImagingHumansMagnetic Resonance ImagingRetrospective StudiesContrast MediaEmergency medicineMagnetic resonance imagingObserver variationPeritonsillar abscessTonsillitis

Identifiers

PMID37872406
PMCPMC10593634
OpenAlexW4387868048

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.