Evidence map›Paper›PMID 37872024›Full record

ArticleTrends in molecular medicine2023

Time-restricted feeding and Alzheimer's disease: you are when you eat.

Melvin W King, Yining Chen, Erik S Musiek

Abstract read
In one paragraph

Article in Trends in molecular medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Observational
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Melvin W KingDepartment of Neurology and Center On Biological Rhythms and Sleep, Washington University School of Medicine, St Louis, MO, USA.
Yining ChenDepartment of Neurology and Center On Biological Rhythms and Sleep, Washington University School of Medicine, St Louis, MO, USA.
Erik S MusiekDepartment of Neurology and Center On Biological Rhythms and Sleep, Washington University School of Medicine, St Louis, MO, USA. Electronic address: musieke@wustl.edu.

Funding

Washington University Nutrition Obesity Research CenterP30DK056341 · NIDDK · WASHINGTON UNIVERSITY · PI Brian N Finck · 1999 to 2026
$30.2M
ROLE OF GLIAL CIRCADIAN CLOCK DYSFUNCTION IN THE PATHOGENESIS OF ALZHEIMER'S DISEASER01AG054517 · NIA · WASHINGTON UNIVERSITY · PI Erik Steven Musiek · 2017 to 2026
$4.5M
NIA NIH HHS R01 AG054517NIDDK NIH HHS P30 DK056341
6 · The paper itself

Abstract

Time-restricted feeding (TRF) has emerged as a means of synchronizing circadian rhythms, which are commonly disrupted in Alzheimer's disease (AD). Whittaker et al. demonstrate that TRF exerts protective effects in two mouse models of AD. We discuss the effects of TRF on brain health and mechanisms linking TRF to neurodegeneration.

Indexed as

Alzheimer DiseaseAnimalsCircadian RhythmDisease Models, AnimalHumansIntermittent FastingMice

Identifiers

PMID37872024
PMCPMC10842495

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.