Evidence map›Paper›PMID 37871852›Full record

ArticleJournal of lipid research2023

Cooperation of acylglycerol hydrolases in neuronal lipolysis.

Liqing Yu

Open access · goldAbstract readComment
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of lipid research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Liqing YuDivision of Endocrinology, Diabetes and Nutrition, Department of Medicine, University of Maryland School of Medicine, Baltimore, MD, USA. Electronic address: lyu@som.umaryland.edu.
University of Maryland, Baltimore · US

Funding

The Role of Adipocyte Lipolysis in ThermoregulationR01DK116496 · NIDDK · UNIVERSITY OF MARYLAND BALTIMORE · PI YU, LIQING · 2018 to 2022
$1.8M
Cellular and Molecular Mechanisms of Fatty Liver DiseaseR01DK111052 · NIDDK · UNIVERSITY OF MARYLAND BALTIMORE · PI YU, LIQING · 2016 to 2019
$1.4M
NIDDK NIH HHS R01 DK111052NIDDK NIH HHS R01 DK116496
6 · The paper itself

Abstract

Genetic and biochemical evidence has established DDHD-domain containing 2 (DDHD2) as the principal triacylglycerol (TAG) hydrolase in neuronal lipolysis of cytosolic lipid droplets. In this issue of Journal of Lipid Research, Hofer et al. report that DDHD2 cooperates with adipose triglyceride lipase, the principal TAG hydrolase in adipose lipolysis, contributing to cytosolic hydrolysis of both TAG and diacylglycerols in murine neuroblastoma cells and primary cortical neurons via different configurations of the lipases. This finding highlights the complexity of cytosolic acylglycerol hydrolysis and raises many new questions in the field of lipid metabolism.

Indexed as

GlyceridesLipolysisAnimalsLipaseMiceNeuronsTriglyceridesGlyceridesLipaseTriglyceridesadipose triglyceride lipasebrainDDHD-domain containing 2hereditary spastic paraplegiahormone sensitive lipaseintracellular phospholipaselipid dropletneuron

Identifiers

PMID37871852
PMCPMC10689277
OpenAlexW4387843413

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.