Evidence map›Paper›PMID 37871809›Full record

ReviewHeart rhythm2024

Up digital and personal: How heart digital twins can transform heart patient care.

Natalia A Trayanova, Adityo Prakosa

Abstract readReview
In one paragraph

Review in Heart rhythm, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. A modelling study of right ventricular growth with valvular regurgitation.Biomechanics and modeling in mechanobiology · 2026
    Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. Review
  11. Review
  12. Review
  13. Automated generation of ablation lesion masks: a unison of electro and optic flow mapping for persistent AF virtual cohorts.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2026
    Article
  14. Review
  15. Review
  16. Article
  17. Current progress of digital twin construction using medical imaging.Journal of applied clinical medical physics · 2025
    Review
  18. Review
  19. Precision cardiac electrophysiology: toward digital twins and beyond.Journal of precision medicine (Amsterdam, Netherlands) · 2025
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Natalia A TrayanovaAlliance for Cardiovascular Diagnostic and Treatment Innovation, Johns Hopkins University, Baltimore, Maryland; Department of Biomedical Engineering, Johns Hopkins University, Baltimore, Maryland. Electronic address: ntrayanova@jhu.edu.
Adityo PrakosaAlliance for Cardiovascular Diagnostic and Treatment Innovation, Johns Hopkins University, Baltimore, Maryland.

Funding

Artificial intelligence analysis of atrial remodeling evolution in patients with atrial fibrillation: Towards optimal ablation strategiesR01HL166759 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI Eugene Kholmovski, David Spragg · 2023 to 2026
$3.2M
Simulation Guidance of Ablation Therapy for Persistent Atrial FibrillationU01HL141074 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI CALKINS, HUGH G, TRAYANOVA, NATALIA A. · 2018 to 2021
$3.1M
Infarct-related Ventricular Tachycardia Mechanisms: From Micro to ClinicalR01HL142496 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI TRAYANOVA, NATALIA A. · 2019 to 2022
$3.1M
NHLBI NIH HHS R01 HL142496NHLBI NIH HHS R01 HL166759NHLBI NIH HHS U01 HL141074
6 · The paper itself

Abstract

Precision medicine is the vision of health care where therapy is tailored to each patient. As part of this vision, digital twinning technology promises to deliver a digital representation of organs or even patients by using tools capable of simulating personal health conditions and predicting patient or disease trajectories on the basis of relationships learned both from data and from biophysics knowledge. Such virtual replicas would update themselves with data from monitoring devices and medical tests and assessments, reflecting dynamically the changes in our health conditions and the responses to treatment. In precision cardiology, the concepts and initial applications of heart digital twins have slowly been gaining popularity and the trust of the clinical community. In this article, we review the advancement in heart digital twinning and its initial translation to the management of heart rhythm disorders.

Indexed as

Atrial FibrillationHeartHumansPatient CareAblationArrhythmiaAtrial fibrillationHeart digital twinsSudden cardiac death risk prediction

Identifiers

PMID37871809
PMCPMC10872898

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.