Evidence map›Paper›PMID 37871303›Full record

ArticleBlood advances2024

Clinical outcomes of older and younger patients treated with loncastuximab tesirine in the LOTIS-2 clinical trial.

Mehdi Hamadani, Alexander Spira, Xiaolei Zhou, Laura Liao, Lei Chen, John Radford, Weiyun Ai, Melhem Solh, Kirit M Ardeshna, Brian Hess and 9 more

Open access · goldAbstract read
In one paragraph

Article in Blood advances, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Article
  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 16 institutions in 4 countries.

Mehdi HamadaniDivision of Hematology and Oncology, BMT & Cellular Therapy Program, Medical College of Wisconsin, Milwaukee, WI.ORCID 0000-0001-5372-510X
Alexander SpiraVirginia Cancer Specialists Research Institute, Fairfax, VA.ORCID 0000-0003-1303-0447
Xiaolei ZhouRTI Health Solutions, Research Triangle Park, NC.ORCID 0000-0002-7992-637X
Laura LiaoADC Therapeutics America Inc, Murray Hill, NJ.
Lei ChenADC Therapeutics America Inc, Murray Hill, NJ.
John RadfordNIHR Clinical Research Facility, University of Manchester and the Christie NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, United Kingdom.ORCID 0000-0001-7898-2786
Weiyun AiHelen Diller Family Comprehensive Cancer Center, University of California, San Francisco, CA.
Melhem SolhBlood and Marrow Transplant Program at Northside Hospital, Atlanta, GA.ORCID 0000-0003-3766-5623
Kirit M ArdeshnaCancer Division, University College London Hospitals NHS Foundation Trust, London, United Kingdom.
Brian HessDepartment of Medicine, Medical University of South Carolina, Charleston, SC.
Paolo F CaimiBlood and Marrow Transplant Program, Taussig Cancer Institute, Cleveland Clinic Foundation, Cleveland, OH.ORCID 0000-0003-1436-0464
Anastasios StathisOncology Institute of Southern Switzerland, Bellinzona, Switzerland.
Carmelo Carlo-StellaDepartment of Biomedical Sciences, Humanitas University, Milan, Italy.ORCID 0000-0003-3144-0124
Juan Pablo AlderuccioSylvester Comprehensive Cancer Center, University of Miami, Miller School of Medicine, Miami, FL.ORCID 0000-0002-2690-3377
Brad KahlDivision of Oncology, Washington University, St. Louis, MO.ORCID 0000-0003-0459-6609
Ying WangADC Therapeutics America Inc, Murray Hill, NJ.
Yajuan QinADC Therapeutics America Inc, Murray Hill, NJ.
Zhiying Cindy XuADC Therapeutics America Inc, Murray Hill, NJ.
Pier Luigi ZinzaniIRCCS Azienda Ospedaliero-Universitaria di Bologna, Istituto di Ematologia Seràgnoli, Bologna, Italy.ORCID 0000-0002-2112-2651
Adc Therapeutics (Switzerland) · CHProvidence College · USCleveland Clinic · USHumanitas University · ITInstitute of Oncology Research · CHIstituto di Ematologia di Bologna · ITManchester Academic Health Science Centre · GBMedical College of Wisconsin · USMedical University of South Carolina · USNorthside Hospital · USRTI Health Solutions · USUniversity College London Hospitals NHS Foundation Trust · GBUniversity of California, San Francisco · USUniversity of Miami · USVirginia Cancer Specialists · USWashington University in St. Louis · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Antibodies, Monoclonal, HumanizedBenzodiazepinesHumansAntibodies, Monoclonal, HumanizedBenzodiazepinesloncastuximab tesirine

Identifiers

PMID37871303
PMCPMC10787240
OpenAlexW4387869205

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.