Evidence map›Paper›PMID 37871213›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2023

Dynamics of

Chao Fang, Mingyu Yang, Yuecheng Tang, Ling Zhang, Hainan Zhao, Hejia Ni, Qingshan Chen, Fanli Meng, Jiming Jiang

Open access · greenAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
12.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 31 citations in OpenAlex.

  1. Article
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  5. Genome evolution through polyploidy: Enhancing plant stress resilience in agriculture.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Review
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  15. Article
  16. Subgenome Dominance in Allotetraploid Actinidia valvata Regulates RNA mAdvanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Article
  17. Functional Genomics: From Soybean to Legume.International journal of molecular sciences · 2025
    Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Chao FangDepartment of Plant Biology, Michigan State University, East Lansing, MI 48824.
Mingyu YangNortheast Institute of Geography and Agroecology, Key Laboratory of Soybean Molecular Design Breeding, Chinese Academy of Sciences, Harbin 150081, China.ORCID 0000-0002-4519-6997
Yuecheng TangNortheast Institute of Geography and Agroecology, Key Laboratory of Soybean Molecular Design Breeding, Chinese Academy of Sciences, Harbin 150081, China.ORCID 0009-0005-3055-1297
Ling ZhangAgro-Biotechnology Research Institute, Jilin Academy of Agricultural Sciences, Changchun 130033, China.ORCID 0000-0002-2708-1176
Hainan ZhaoDepartment of Plant Biology, Michigan State University, East Lansing, MI 48824.ORCID 0000-0003-0235-6126
Hejia NiKey Laboratory of Soybean Biology in Chinese Ministry of Education, Northeast Agricultural University, Harbin 150030, China.ORCID 0000-0002-2634-5360
Qingshan ChenKey Laboratory of Soybean Biology in Chinese Ministry of Education, Northeast Agricultural University, Harbin 150030, China.ORCID 0000-0002-3714-9066
Fanli MengNortheast Institute of Geography and Agroecology, Key Laboratory of Soybean Molecular Design Breeding, Chinese Academy of Sciences, Harbin 150081, China.ORCID 0000-0002-0942-1798
Jiming JiangDepartment of Plant Biology, Michigan State University, East Lansing, MI 48824.
Northeast Agricultural University · CNMichigan State University · USChinese Academy of Sciences · CNJilin Academy of Agricultural Sciences · CN

Funding

MOST | National Natural Science Foundation of China (NSFC) 32172032National Key R & D Program of China 2021YFF1001202National Project of China CARS-04National Science Foundation (NSF) ISO-2029959National Science Foundation (NSF) MCB-1412948
6 · The paper itself

Abstract

Transcriptional divergence of duplicated genes after whole genome duplication (WGD) has been described in many plant lineages and is often associated with subgenome dominance, a genome-wide mechanism. However, it is unknown what underlies the transcriptional divergence of duplicated genes in polyploid species that lack subgenome dominance. Soybean is a paleotetraploid with a WGD that occurred 5 to 13 Mya. Approximately 50% of the duplicated genes retained from this WGD exhibit transcriptional divergence. We developed accessible chromatin region (ACR) datasets from leaf, flower, and seed tissues using MNase-hypersensitivity sequencing. We validated enhancer function of several ACRs associated with known genes using CRISPR/Cas9-mediated genome editing. The ACR datasets were used to examine and correlate the transcriptional patterns of 17,111 pairs of duplicated genes in different tissues. We demonstrate that ACR dynamics are correlated with divergence of both expression level and tissue specificity of individual gene pairs. Gain or loss of flanking ACRs and mutation of

Indexed as

Evolution, MolecularGlycine maxBase SequenceGene DuplicationGenes, DuplicateGenomeGenome, Plantaccessible chromatin regionCRISPR/Casgene duplicationMNase hypersensitivitytranscriptional divergence

Identifiers

PMID37871213
PMCPMC10622917
OpenAlexW4387871805

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.