Evidence map›Paper›PMID 37871205›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2023

Activity-induced MeCP2 phosphorylation regulates retinogeniculate synapse refinement.

Christopher P Tzeng, Tess Whitwam, Lisa D Boxer, Emmy Li, Andrew Silberfeld, Sara Trowbridge, Kevin Mei, Cindy Lin, Rebecca Shamah, Eric C Griffith and 3 more

Open access · greenAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 9 citations in OpenAlex.

  1. MECP2Science China. Life sciences · 2026
    Article
  2. Article
  3. Article
  4. Review
  5. The CaInternational journal of molecular sciences · 2025
    Review
  6. Article
  7. Article
  8. Review
  9. Activity-induced MeCP2 phosphorylation regulates retinogeniculate synapse refinement.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Christopher P Tzeng *Department of Neurobiology, Harvard Medical School, Boston, MA 02115.ORCID 0000-0003-4734-6298
Tess Whitwam *Department of Neurobiology, Harvard Medical School, Boston, MA 02115.ORCID 0000-0001-7076-7811
Lisa D Boxer *Department of Neurobiology, Harvard Medical School, Boston, MA 02115.ORCID 0000-0002-4402-1060
Emmy LiDepartment of Neurobiology, Harvard Medical School, Boston, MA 02115.
Andrew SilberfeldDepartment of Neurobiology, Harvard Medical School, Boston, MA 02115.
Sara TrowbridgeDepartment of Neurobiology, Harvard Medical School, Boston, MA 02115.
Kevin MeiDepartment of Neurobiology, Harvard Medical School, Boston, MA 02115.
Cindy LinDepartment of Neurobiology, Harvard Medical School, Boston, MA 02115.
Rebecca ShamahDepartment of Neurobiology, Harvard Medical School, Boston, MA 02115.
Eric C GriffithDepartment of Neurobiology, Harvard Medical School, Boston, MA 02115.ORCID 0000-0003-0428-3215
William RenthalDepartment of Neurobiology, Harvard Medical School, Boston, MA 02115.
Chinfei ChenDepartment of Neurology, F.M. Kirby Neurobiology Center, Children's Hospital, Boston, MA 02115.
Michael E GreenbergDepartment of Neurobiology, Harvard Medical School, Boston, MA 02115.ORCID 0000-0003-1380-2160
Harvard University · USBoston Children's Hospital · US

Funding

Short-term plasticity of the retinogeniculate synapseR01EY013613 · NEI · CHILDREN'S HOSPITAL BOSTON · PI Chinfei Chen · 2003 to 2026
$10.3M
Genetic Analysis and Manipulation Core (GAEC)P50HD105351 · NICHD · BOSTON CHILDREN'S HOSPITAL · PI SCOTT Loren POMEROY, MUSTAFA SAHIN · 2021 to 2026
$9.4M
Neuronal Activity-Dependent Regulation of MeCP2R01NS048276 · NINDS · HARVARD MEDICAL SCHOOL · PI GREENBERG, MICHAEL ELDON · 2004 to 2019
$6.9M
Characterization of MeCP2-dependent gene regulation with temporal and mechanistic precisionK99NS112415 · NINDS · HARVARD MEDICAL SCHOOL · PI BOXER, LISA D. · 2019 to 2021
$268k
NEI NIH HHS R01 EY013613NICHD NIH HHS P50 HD105351NINDS NIH HHS K99 NS112415NINDS NIH HHS R01 NS048276
6 · The paper itself

Abstract

Mutations in

Indexed as

Methyl-CpG-Binding Protein 2Rett SyndromeAnimalsBrainDisease Models, AnimalFemaleMiceMice, KnockoutNeuronsPhosphorylationSynapsesMethyl-CpG-Binding Protein 2LGNMeCP2phosphorylationRett syndromesynapse refinement

Identifiers

PMID37871205
PMCPMC10623012
OpenAlexW4387871756

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.