Evidence map›Paper›PMID 37871133›Full record

ArticlePLoS computational biology2023

Tissue Forge: Interactive biological and biophysics simulation environment.

T J Sego, James P Sluka, Herbert M Sauro, James A Glazier

Abstract read
In one paragraph

Article in PLoS computational biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
  3. Personalizing computational models to construct medical digital twins.Journal of the Royal Society, Interface · 2025
    Article
  4. Article
  5. Personalizing computational models to construct medical digital twins.bioRxiv : the preprint server for biology · 2024
    Article
  6. Article
  7. Review
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

T J SegoDepartment of Medicine, University of Florida, Gainesville, Florida, United States of America.ORCID 0000-0002-4274-656X
James P SlukaDepartment of Intelligent Systems Engineering and Biocomplexity Institute, Indiana University, Bloomington, Indiana, United States of America.ORCID 0000-0002-5901-1404
Herbert M SauroDepartment of Bioengineering, University of Washington, Seattle, Washington, United States of America.
James A GlazierDepartment of Intelligent Systems Engineering and Biocomplexity Institute, Indiana University, Bloomington, Indiana, United States of America.ORCID 0000-0003-3634-190X

Funding

TR&D3: Standards and Tools for Simulator Composition and Credibility portalP41EB023912 · NIBIB · UNIVERSITY OF WASHINGTON · PI Ion I. Moraru, HERBERT M. SAURO · 2018 to 2026
$11.4M
Competitive Renewal of Development, Improvement and Extension of the Tissue Simulation Environment - CompuCell3DR01GM122424 · NIGMS · TRUSTEES OF INDIANA UNIVERSITY · PI GLAZIER, JAMES ALEXANDER · 2017 to 2020
$1.7M
Dissemination of libRoadRunner and CompuCell3DU24EB028887 · NIBIB · UNIVERSITY OF WASHINGTON · PI GLAZIER, JAMES ALEXANDER, SAURO, HERBERT M. · 2019 to 2023
$1.5M
EPA RD840027NIBIB NIH HHS P41 EB023912NIBIB NIH HHS U24 EB028887NIGMS NIH HHS R01 GM122424
6 · The paper itself

Abstract

Tissue Forge is an open-source interactive environment for particle-based physics, chemistry and biology modeling and simulation. Tissue Forge allows users to create, simulate and explore models and virtual experiments based on soft condensed matter physics at multiple scales, from the molecular to the multicellular, using a simple, consistent interface. While Tissue Forge is designed to simplify solving problems in complex subcellular, cellular and tissue biophysics, it supports applications ranging from classic molecular dynamics to agent-based multicellular systems with dynamic populations. Tissue Forge users can build and interact with models and simulations in real-time and change simulation details during execution, or execute simulations off-screen and/or remotely in high-performance computing environments. Tissue Forge provides a growing library of built-in model components along with support for user-specified models during the development and application of custom, agent-based models. Tissue Forge includes an extensive Python API for model and simulation specification via Python scripts, an IPython console and a Jupyter Notebook, as well as C and C++ APIs for integrated applications with other software tools. Tissue Forge supports installations on 64-bit Windows, Linux and MacOS systems and is available for local installation via conda.

Indexed as

PhysicsSoftwareBiophysicsComputer Simulation

Identifiers

PMID37871133
PMCPMC10621971

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.