Evidence map›Paper›PMID 37871102›Full record

ArticlePloS one2023

Diagnostic accuracy of using capnography in verification of nasogastric tube placement among adult patients in hospital settings: Protocol of a diagnostic study.

Janita Pak Chun Chau, Danny Wah Kun Tong, Suzanne Hoi Shan Lo, Savina Yee Man Sze, Molly Lai Mei Kwok, Peter Chi Keung Lai, Harris Kai Cheong Lam, Josephine Yuen Man Chung, Xu Liu, Wai Tong Chien and 1 more

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in PloS one, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05817864 (Diagnostic Accuracy of Using Capnography in Verification of Nasogastric Tube Placement in Hospital Settings), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05817864 recruitingnot on this map

Diagnostic Accuracy of Using Capnography in Verification of Nasogastric Tube Placement in Hospital Settings

TypeobservationalSponsorChinese University of Hong KongRan2023 to 2025Enrolled390ConditionsCapnography, Nasogastric Tube, Diagnostic AccuracyArmsCapnography
3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 2 countries.

Janita Pak Chun ChauNethersole School of Nursing, The Chinese University of Hong Kong, Hong Kong, Hong Kong.ORCID 0000-0002-3750-7396
Danny Wah Kun TongNursing Services Department, Hospital Authority Hong Kong, Hong Kong, Hong Kong.
Suzanne Hoi Shan LoNethersole School of Nursing, The Chinese University of Hong Kong, Hong Kong, Hong Kong.
Savina Yee Man SzeShatin Hospital, Hospital Authority Hong Kong, Hong Kong, Hong Kong.
Molly Lai Mei KwokNursing Services Department, Hospital Authority Hong Kong, Hong Kong, Hong Kong.
Peter Chi Keung LaiQueen Mary Hospital, Hospital Authority Hong Kong, Hong Kong, Hong Kong.
Harris Kai Cheong LamRuttonjee and Tang Shiu Kin Hospitals, Hospital Authority Hong Kong, Hong Kong, Hong Kong.
Josephine Yuen Man ChungPrince of Wales Hospital, Hospital Authority Hong Kong, Hong Kong, Hong Kong.
Xu LiuNethersole School of Nursing, The Chinese University of Hong Kong, Hong Kong, Hong Kong.
Wai Tong ChienNethersole School of Nursing, The Chinese University of Hong Kong, Hong Kong, Hong Kong.ORCID 0000-0001-5321-5791
Kai Chow ChoiNethersole School of Nursing, The Chinese University of Hong Kong, Hong Kong, Hong Kong.
Hospital Authority · HKChinese University of Hong Kong · HK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo determine the diagnostic accuracy of end-tidal carbon dioxide (ETCO2) detection using capnography for verifying the correct placement of nasogastric tubes (NGTs) among adult patients in hospital settings. MATERIALS AND

methodsA prospective observational diagnostic study will be conducted. Patients ≥ 18-year-old and requiring the insertion of an NGT will be recruited using a convenience sampling method from 39 general medical and geriatric wards, intensive care units, accident and emergency departments, and subacute/rehabilitation/infirmary wards in 21 acute or subacute/convalescent/extended care hospitals. ETCO2 detection by sidestream capnography, which indicates an airway intubation of an NGT when a capnogram waveform or an ETCO2 level > 10mmHg (1.33 kPa) occurs, will serve as the index test. The reference standards will be the X-ray performed and pH value of gastric aspiration (pH ≤ 5.5) after the index test. Each participant will be included only once. Sensitivity, specificity, positive predictive value, negative predictive value, and area under the receiver operating characteristic curve of capnography will be calculated to assess the diagnostic performance of capnography. The variability in diagnostic accuracy in participants with different characteristics will be explored by using chi-squared or Fisher's exact tests. The time spent and the cost of the tests will be compared using the paired t-test. All statistical tests will be two-sided with a level of significance set at 0.05. DISCUSSION: This study will provide evidence on the diagnostic accuracy of capnography in verifying NGT placement and its applicability to patients in hospitals settings, since this evidence is limited in the current literature. In addition, it will help identify the optimal combination of tests in verifying the correct placement of NGTs and inform the update of clinical practice guidelines and stakeholders' decisions on the adoption of ETCO2 detection as a routine method for verifying NGT placement.

trial registrationClinicalTrials.gov ID: NCT05817864.

Indexed as

CapnographyCarbon DioxideAdolescentAdultAgedHospitalsHumansIntensive Care UnitsIntubation, GastrointestinalObservational Studies as TopicCarbon Dioxide

Identifiers

PMID37871102
PMCPMC10593214
OpenAlexW4387881062

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.