Evidence map›Paper›PMID 37870730›Full record

ArticleJournal of racial and ethnic health disparities2024

Association Between Race, Cardiology Care, and the Receipt of Guideline-Directed Medical Therapy in Peripartum Cardiomyopathy.

Ikeoluwapo Kendra Bolakale-Rufai, Shannon M Knapp, Amber E Johnson, LaPrincess Brewer, Selma Mohammed, Daniel Addison, Sula Mazimba, Brownsyne Tucker-Edmonds, Khadijah Breathett

Open access · greenAbstract read
In one paragraph

Article in Journal of racial and ethnic health disparities, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
  3. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 7 institutions in 1 country.

Ikeoluwapo Kendra Bolakale-RufaiDivision of Cardiovascular Medicine, Krannert Cardiovascular Research Center, Indiana University, 1800 North Capitol Avenue, Indianapolis, IN, 46202, USA.
Shannon M KnappDivision of Cardiovascular Medicine, Krannert Cardiovascular Research Center, Indiana University, 1800 North Capitol Avenue, Indianapolis, IN, 46202, USA.
Amber E JohnsonDivision of Cardiology, University of Chicago, Chicago, IL, USA.
LaPrincess BrewerDepartment of Cardiovascular Medicine, Mayo Clinic, Rochester, USA.
Selma MohammedDivision of Cardiology, Creighton University, Omaha, USA.
Daniel AddisonDivision of Cardiovascular Medicine, The Ohio State University, Columbus, USA.
Sula MazimbaDivision of Cardiovascular Medicine, University of Virginia, Charlottesville, USA.
Brownsyne Tucker-EdmondsDepartment of Obstetrics and Gynecology, Indiana University, Indianapolis, USA.
Khadijah BreathettDivision of Cardiovascular Medicine, Krannert Cardiovascular Research Center, Indiana University, 1800 North Capitol Avenue, Indianapolis, IN, 46202, USA. kbreath@iu.edu.ORCID 0000-0001-5397-6419
Indiana University – Purdue University Indianapolis · USCreighton University · USIndiana University Health · USMayo Clinic · USThe Ohio State University · USUniversity of Chicago · USUniversity of Virginia · US

Funding

Seeking Objectivity in Allocation of Advanced Heart Failure (SOCIAL HF) Therapies TrialR01HL159216 · NHLBI · INDIANA UNIVERSITY INDIANAPOLIS · PI BREATHETT, KHADIJAH · 2022 to 2025
$2.6M
Seeking Objectivity in Allocation of Advanced Heart Failure (SOCIAL HF) Therapies TrialR56HL159216 · NHLBI · UNIVERSITY OF ARIZONA · PI BREATHETT, KHADIJAH · 2021 to 2021
$906k
Addressing Individual Provider Bias and Group Decision-Making in Selection of Advanced Heart Failure Therapies in Racial/Ethnic MinoritiesK01HL142848 · NHLBI · UNIVERSITY OF ARIZONA · PI BREATHETT, KHADIJAH · 2018 to 2021
$858k
NHLBI NIH HHS K01 HL142848NHLBI NIH HHS L30 HL148881NHLBI NIH HHS R01 HL159216NHLBI NIH HHS R56 HL159216
6 · The paper itself

Abstract

backgroundBlack patients with peripartum cardiomyopathy (PPCM) have disproportionately worse outcomes than White patients, possibly related to variable involvement of cardiovascular specialists in their clinical care. We sought to determine whether race was associated with cardiology involvement in clinical care during inpatient admission and whether cardiology involvement in care was associated with higher claims of guideline-directed medical therapy (GDMT) a week after hospital discharge.

methodsUsing Optum's de-identified Clinformatics® Data Mart (CDM), we included Black and White patients' first hospital admission for PPCM from 2008 to 2021. Cardiology involvement in clinical care was defined as the receipt of attending care from a cardiovascular specialist during admission. GDMT included beta-blockers (BB) for all patients and triple therapy (BB, angiotensin-responsive medications, and mineralocorticoid receptor antagonists) for non-pregnant patients. Logistic regression was used to determine the associations between cardiology involvement in clinical care during admission and (1) patient race and (2) GDMT prescription, adjusting for age and comorbidities.

resultsAmong 668 patients (32.6% Black, 67.4% White, 93.3% commercially insured), there was no significant difference in the odds of cardiology involvement in clinical care by race (aOR: 1.41; 95%CI: 0.87-2.33, P=0.17). Inpatient cardiology care was associated with 2.75 times increased odds of having a prescription claim for GDMT (BB) for White patients (aOR: 2.75; 95%CI 1.50-5.06, P=0.001), and the estimated effect size was similar but not statistically significant for Black patients (aOR: 2.20, 95% CI, 0.84-5.71, P=0.11). The interaction between race and cardiology involvement in clinical care was not statistically significant for the receipt of BB prescription. Among 274 non-pregnant patients with PPCM (37.2% Black, 62.8% White), 5.8% received triple GDMT. Of these, none of the Black patients lacking cardiology care had triple GDMT. However, cardiology involvement in care was not significantly associated with triple GDMT for either race.

conclusionsAmong a commercially insured population within PPCM, race was not associated with cardiology involvement in clinical care during hospitalization. However, cardiology involvement in care was associated with significantly higher odds of prescription claims for BB for only White patients. Additional strategies are needed to support equitable GDMT prescription.

Indexed as

Black or African AmericanCardiomyopathiesPeripartum PeriodWhiteAdrenergic beta-AntagonistsAdultCardiologyFemaleGuideline AdherenceHealthcare DisparitiesHumansPractice Guidelines as TopicPregnancyPregnancy Complications, CardiovascularAdrenergic beta-AntagonistsGuideline-directed medical therapyHeart failureInsurancePeripartum cardiomyopathyPregnancyRacial disparitiesSocial determinants

Identifiers

PMID37870730
PMCPMC11035491
OpenAlexW4387866397

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.