Evidence map›Paper›PMID 37870611›Full record

SynthesisEuropean journal of pediatrics2024

Shorter versus longer duration of antibiotic treatment in children with bacterial meningitis: a systematic review and meta-analysis.

Renan Yuji Ura Sudo, Maria Carrijo Cunha Câmara, Sofia Vezzani Kieling, Isabela Reis Marques, Yasmin Mesquita, Blake Earl Piepenbrink, Paula Chaves Mari

Open access · hybridAbstract readMeta-AnalysisSystematic Review
PubMed Publisher
In one paragraph

Synthesis in European journal of pediatrics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.7field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 7 institutions in 3 countries.

Renan Yuji Ura SudoDivision of Medicine, Federal University of Grande Dourados, Dourados, MS, Brazil. yujinah_ry@hotmail.com.ORCID http://orcid.org/0000-0001-8117-2784
Maria Carrijo Cunha CâmaraDivision of Medicine, Federal University of Goiás, Goiânia, GO, Brazil.ORCID http://orcid.org/0000-0002-0542-1475
Sofia Vezzani KielingDivision of Medicine, University of Vale do Rio dos Sinos, São Leopoldo, RJ, Brazil.ORCID http://orcid.org/0000-0001-6636-2715
Isabela Reis MarquesDivision of Medicine, Universitat Internacional de Catalunya, Barcelona, CAT, Spain.ORCID https://orcid.org/0000-0002-5160-0650
Yasmin MesquitaDivision of Medicine, Federal University of Rio de Janeiro, Macaé, RJ, Brazil.ORCID http://orcid.org/0000-0001-8607-6302
Blake Earl PiepenbrinkDivision of Internal Medicine, Primary Care, University of Connecticut, Farmington, CT, USA.ORCID http://orcid.org/0000-0003-1229-9225
Paula Chaves MariPediatric Division, Cleveland Clinic Children's Hospital, Cleveland, OH, USA.ORCID http://orcid.org/0000-0002-6063-0050
Cleveland Clinic · USUniversidade do Vale do Rio dos Sinos · BRUniversidade Federal da Grande Dourados · BRUniversidade Federal de Goiás · BRUniversidade Federal do Rio de Janeiro · BRUniversitat Internacional de Catalunya · ESUniversity of Connecticut · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The optimal duration of antibiotic treatment for the most common bacterial meningitis etiologies in the pediatric population, namely Streptococcus pneumoniae, Haemophilus influenzae, and Neisseria meningitidis, is not well-established in the literature. Therefore, we aimed to perform an updated meta-analysis comparing shorter versus longer antibiotic treatment in children with meningitis. PubMed, EMBASE, and Cochrane databases were searched for randomized controlled trials (RCTs) that compared shorter (up to 7 days) versus longer (10 days or double the days of the equivalent short course) duration of antibiotic treatment in children with meningitis and reported the outcomes of treatment failure, death, neurologic sequelae, non-neurologic complications, hearing impairment, nosocomial infection, and relapse. Heterogeneity was examined with I

Indexed as

Anti-Bacterial AgentsDuration of TherapyMeningitis, BacterialAdolescentChildChild, PreschoolDrug Administration ScheduleHumansInfantRandomized Controlled Trials as TopicTreatment OutcomeAnti-Bacterial AgentsAntibioticBacterial meningitisChildrenDuration of therapyPediatric populationShorter versus longer therapy

Identifiers

PMID37870611
OpenAlexW4387866087

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.