Evidence map›Paper›PMID 37870542›Full record

ArticleThe American journal of managed care2023

Choosing Wisely interventions to reduce antibiotic overuse in the safety net.

Richard K Leuchter, Catherine A Sarkisian, Rebecca Trotzky-Sirr, Eric K Wei, Carmen A Carrillo, Sitaram Vangala, Charles Coffey, Brad Spellberg, Oleg Melamed, Arthur C Jeng and 1 more

Open access · greenAbstract read
In one paragraph

Article in The American journal of managed care, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Trial
  2. Financial incentives and information provision for post-pandemic primary care quality recovery: a longitudinal study in Catalonia.The British journal of general practice : the journal of the Royal College of General Practitioners · 2026
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Richard K LeuchterDivision of General Internal Medicine & Health Services Research, Department of Internal Medicine, David Geffen School of Medicine at UCLA, 1100 Glendon Ave, Ste 726, Los Angeles, CA 90024. Email: rleuchter@mednet.ucla.edu.
Catherine A Sarkisian
Rebecca Trotzky-Sirr
Eric K Wei
Carmen A Carrillo
Sitaram Vangala
Charles Coffey
Brad Spellberg
Oleg Melamed
Arthur C Jeng
John N Mafi
UCLA Health · US

Funding

UCLA Clinical Translational Science InstituteUL1TR001881 · NCATS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI ARLEEN F. BROWN, ARASH NAEIM · 2016 to 2026
$118.1M
The Center for Health Improvement of Minority ElderlyP30AG021684 · NIA · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Homero Erwin del Pino · 2002 to 2026
$19.7M
The Effect of Nanoparticle Encapsulated Resveratrol on Treatment of PeriodontitisKL2TR001882 · NCATS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Elizabeta Nemeth · 2016 to 2026
$13.1M
Midcareer Award in Patient-Oriented Community-Academic Partnered Aging ResearchK24AG047899 · NIA · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI SARKISIAN, CATHERINE A · 2014 to 2025
$2.0M
Leveraging Electronic Health Records to Measure and Reduce Harmful, Low-Value Care Among Older AdultsK76AG064392 · NIA · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI MAFI, JOHN · 2020 to 2024
$1.2M
The University of California - Los Angeles (UCLA) Resident Scientist Training Program (RSTP)R38HL143614 · NHLBI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI AJIJOLA, OLUJIMI A, DEMER, LINDA L. · 2020 to 2023
$1.1M
Using Machine Learning and Patient-Reported Outcomes to Identify Unnecessary HospitalizationsK38HL164955 · NHLBI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI LEUCHTER, RICHARD K · 2022 to 2023
$224k
NCATS NIH HHS KL2 TR001882NCATS NIH HHS UL1 TR001881NHLBI NIH HHS K38 HL164955NHLBI NIH HHS L60 HL170940NHLBI NIH HHS R38 HL143614NIA NIH HHS K24 AG047899NIA NIH HHS K76 AG064392NIA NIH HHS P30 AG021684
6 · The paper itself

Abstract

objectivesPhysician pay-for-performance (P4P) programs frequently target inappropriate antibiotics. Yet little is known about P4P programs' effects on antibiotic prescribing among safety-net populations at risk for unintended harms from reducing care. We evaluated effects of P4P-motivated interventions to reduce antibiotic prescriptions for safety-net patients with acute respiratory tract infections (ARTIs). STUDY

designInterrupted time series.

methodsA nonrandomized intervention (5/28/2015-2/1/2018) was conducted at 2 large academic safety-net hospitals: Los Angeles County+University of Southern California (LAC+USC) and Olive View-UCLA (OV-UCLA). In response to California's 2016 P4P program to reduce antibiotics for acute bronchitis, 5 staggered Choosing Wisely-based interventions were launched in combination: audit and feedback, clinician education, suggested alternatives, procalcitonin, and public commitment. We also assessed 5 unintended effects: reductions in Healthcare Effectiveness Data and Information Set (HEDIS)-appropriate prescribing, diagnosis shifting, substituting antibiotics with steroids, increasing antibiotics for ARTIs not penalized by the P4P program, and inappropriate withholding of antibiotics.

resultsAmong 3583 consecutive patients with ARTIs, mean antibiotic prescribing rates for ARTIs decreased from 35.9% to 22.9% (odds ratio [OR], 0.60; 95% CI, 0.39-0.93) at LAC+USC and from 48.7% to 27.3% (OR, 0.81; 95% CI, 0.70-0.93) at OV-UCLA after the intervention. HEDIS-inappropriate prescribing rates decreased from 28.9% to 19.7% (OR, 0.69; 95% CI, 0.39-1.21) at LAC+USC and from 40.9% to 12.5% (OR, 0.72; 95% CI, 0.59-0.88) at OV-UCLA. There was no evidence of unintended consequences.

conclusionsThese real-world multicomponent interventions responding to P4P incentives were associated with substantial reductions in antibiotic prescriptions for ARTIs in 2 safety-net health systems without unintended harms.

Indexed as

PhysiciansRespiratory Tract InfectionsAnti-Bacterial AgentsHumansPractice Patterns, Physicians'Reimbursement, IncentiveAnti-Bacterial Agents

Identifiers

PMID37870542
PMCPMC10994234
OpenAlexW4387787018

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.