ArticleClinical advances in periodontics2024
Human platelet-derived growth factor-BB (rhPDGF-BB) with collagen matrix for sinus elevation without using a bone graft.
Article in Clinical advances in periodontics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed, 3 citations in OpenAlex.
- Clinical Indications and Outcomes of Sinus Floor Augmentation With Bone Substitutes: An Evidence-Based Review.Clinical implant dentistry and related research · 2025Review
- Concentrated Growth Factors and Bone Grafting in Maxillary Sinus Lift: A Systematic Review.International journal of dentistry · 2025Review
- Human platelet-derived growth factor-BB (rhPDGF-BB) with collagen matrix for sinus elevation without using a bone graft.Clinical advances in periodontics · 2024Article
- The Impact of Socket Shield and Implant Surface Modification With Platelet-Derived Growth Factor on Osseointegration.Cureus · 2024Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThis case report involves a 38-year-old male who presented to the clinic after experiencing complications from a tooth extraction, including a dislodged root segment in the sinus, a sinus wall fenestration on the palate, a residual bone height (RBH) of 3 mm, and inadequate healing of the soft tissue. He presented for implant placement.
methodsRecombinant human platelet-derived growth factor-BB (rh-PDGF-BB) was applied to a wound dressing material and placed in the sinus cavity alongside a 4.8 × 10 mm dental implant (Straumann SP, Straumann, Andover, MA, USA.). As documented in the literature, a graftless sinus lift via a lateral window was performed using a split-thickness flap technique to elevate the sinus membrane, re-establish its integrity, and restore its barrier function.
resultsAn 8-month cone beam computed tomography assessment showed a 6.2 mm vertical bone gain and complete implant coverage.
conclusionThis approach provided a successful alternative to shorten treatment duration and achieve favorable radiographic outcomes during early healing. KEY POINTS: The use of rhPDGF-BB and a collagen matrix in a sinus lift procedure emerges as a practical therapeutic option when grafting might lack predictability and notably consume more treatment time, while also achieving the desired bone height when used with a simultaneously placed implant.
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