Evidence map›Paper›PMID 37870416›Full record

ArticleAmerican journal of respiratory and critical care medicine2023

The Interaction of Acute Kidney Injury with Resuscitation Strategy in Sepsis: A Secondary Analysis of a Multicenter, Phase 3, Randomized Clinical Trial (CLOVERS).

Ayesha Khader, Leila R Zelnick, Neha A Sathe, Bryan R Kestenbaum, Jonathan Himmelfarb, Nicholas J Johnson, Nathan I Shapiro, Ivor S Douglas, Catherine L Hough, Pavan K Bhatraju

Open access · greenAbstract readLetter
In one paragraph

Article in American journal of respiratory and critical care medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Trial
  2. Molecular Phenotyping of Sepsis and Differential Response to Fluid Resuscitation.American journal of respiratory and critical care medicine · 2025
    Trial
  3. Trial
  4. Observational
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 2 countries.

Ayesha KhaderDivision of Pulmonary, Critical Care and Sleep Medicine.ORCID 0009-0008-4940-0386
Leila R ZelnickKidney Research Institute, Division of Nephrology, Department of Medicine.
Neha A SatheDivision of Pulmonary, Critical Care and Sleep Medicine.ORCID 0000-0002-9072-0559
Bryan R KestenbaumKidney Research Institute, Division of Nephrology, Department of Medicine.
Jonathan HimmelfarbKidney Research Institute, Division of Nephrology, Department of Medicine.
Nicholas J JohnsonDivision of Pulmonary, Critical Care and Sleep Medicine.ORCID 0000-0001-9915-0591
Nathan I ShapiroDepartment of Emergency Medicine, Beth Israel Deaconess Medical Center, Boston, Massachusetts.
Ivor S DouglasPulmonary Science and Critical Care Medicine, Denver Health Medical Center and University of Colorado, Anschutz Medical Campus, Denver, Colorado; and.ORCID 0000-0002-4541-1431
Catherine L HoughDivision of Pulmonary, Allergy, and Critical Care Medicine, Oregon Health & Science University, Portland, Oregon.
Pavan K BhatrajuDivision of Pulmonary, Critical Care and Sleep Medicine.
Kidney Research UK · GBSleepMed · USBeth Israel Deaconess Medical Center · USDenver Health Medical Center · USOregon Health & Science University · USUniversity of Washington · US

Funding

CCC for NHLBI Prevention and Early Treatment of Acute Lung Injury PETAL NetworkU01HL123009 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI FOULKES, ANDREA S, THOMPSON, BOYD TAYLOR · 2014 to 2021
$67.2M
Identification and Validation of Biological Sub-phenotypes of Sepsis-induced Acute Kidney Injury: A Precision Medicine Approach to Improve Clinical OutcomesR01DK133177 · NIDDK · UNIVERSITY OF WASHINGTON · PI Pavan Kumar Bhatraju · 2022 to 2026
$2.6M
The Assessment of Acute Kidney Injury Sub-phenotypes in the Intensive Care UnitK23DK116967 · NIDDK · UNIVERSITY OF WASHINGTON · PI BHATRAJU, PAVAN KUMAR · 2019 to 2023
$938k
NHLBI NIH HHS U01 HL123009NIDDK NIH HHS K23 DK116967NIDDK NIH HHS K23DK116967NIDDK NIH HHS R01 DK133177NIDDK NIH HHS R01DK133177
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Acute Kidney InjurySepsisClinical Trials, Phase III as TopicFluid TherapyHumansMedicagoMulticenter Studies as TopicRandomized Controlled Trials as TopicResuscitation

Identifiers

PMID37870416
PMCPMC10765399
OpenAlexW4387866164

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.