ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2023
Semi-Telechelic Polymers from Mechanochemical C─C Bond Activation.
Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Liquid-assisted grinding enables a direct mechanochemical functionalization of polystyrene waste.Chemical science · 2024Article
- Semi-Telechelic Polymers from Mechanochemical C─C Bond Activation.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2023Article
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Authors and funding
2 authors.
Funding
Abstract
Unstrained C─C bond activation is attained in homopolymers through mechanochemical bond scission followed by functionalization to yield mostly semi-telechelic polymer chains. Ball milling poly(ethylene oxide) (PEO) in the presence of 1-(bromoacetyl)pyrene (BAPy) yields the pyrene terminated PEO. Similarly, milling with 2,4'-dibromoacetophenone followed by Suzuki coupling allows the introduction of various aryl end groups. PEOs with a molecular weight below 20 kDa show no functionalization, supporting a mechanochemical mechanism. The protocol is also tested with doxorubicin, yielding the drug-polymer conjugate. PEO halogenation is also demonstrated by milling PEO with iodine, N-bromosuccinimide, or N-iodosuccinimide, which can then be reacted with an amine substituted anthracene. Grinding additional carbon polymers with BAPy indicates that this functionalization method is general for different polymer chemistries.
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